Cooperative catalysis : designing efficient catalysts for synthesis / edited by René Peters.

Format:

Book

Contributor:

Peters, René, editor.

Language:

English

Subjects (All):

Catalysis.

Catalysts.

Physical Description:

1 online resource (452 p.)

Edition:

1st ed.

Place of Publication:

Weinheim, Germany : Wiley-VCH, 2015.

Language Note:

English

Summary:

Written by experts in the field, this is a much-needed overview of the rapidly emerging field of cooperative catalysis. The authors focus on the design and development of novel high-performance catalysts for applications in organic synthesis (particularly asymmetric synthesis), covering a broad range of topics, from the latest progress in Lewis acid / Br?nsted base catalysis to e.g. metal-assisted organocatalysis, cooperative metal/enzyme catalysis, and cooperative catalysis in polymerization reactions and on solid surfaces. The chapters are classified according to the type of cooperating acti

Contents:

Cooperative Catalysis; Contents; Preface; Acknowledgments; List of Contributors; Chapter 1 Lewis Acid-Bronsted Base Catalysis; 1.1 Introduction; 1.2 Lewis Acid-Bronsted Base Catalysis in Metalloenzymes; 1.3 Hard Lewis Acid-Bronsted Base Cooperative Catalysis; 1.3.1 Cooperative Catalysts Based on a 1,1'-Binaphthol Ligand Platform; 1.3.1.1 Heterobimetallic Catalysts; 1.3.1.2 Cooperative Catalysts Based on Linked-BINOL; 1.3.2 Cooperative Catalysts Based on a Salen and Schiff Base Ligand Platform; 1.3.3 Cooperative Catalysts Based on a Ligand Platform Derived from Amino Acids

1.4 Soft Lewis Acid-Bronsted Base Cooperative Catalysis1.5 Conclusion; References; Chapter 2 Lewis Acid-Lewis Base Catalysis; 2.1 Introduction; 2.2 Lewis Acid and Lewis Base Activation; 2.2.1 Modes of Activation; 2.2.2 Self-Quenching; 2.3 Addition to Carbonyl Compounds; 2.3.1 Reduction of Ketones; 2.3.2 Alkylation of Aldehydes and Ketones; 2.3.3 Allylation of Aldehydes and Ketones; 2.3.3.1 Lewis Acid/Lewis Base Activation; 2.3.3.2 Lewis Base Nucleophilic/Electrophilic Activation of Allylsilanes; 2.3.4 Cyanation of Aldehydes, Ketones, and Imines; 2.3.4.1 Silylcyanation

2.3.4.2 Cyanoformylation and Cyanophosphorylation2.3.4.3 Cyanoacylation; 2.4 Condensation Reactions; 2.4.1 Aldol Reactions; 2.4.2 Mannich Reactions; 2.5 Morita-Baylis-Hillman Reactions; 2.6 Epoxide Openings; 2.6.1 Coupling with CO2 and CS2; 2.7 Cyclization Reactions; 2.7.1 [2+2] Cycloadditions; 2.7.2 [3+2] Cycloadditions; 2.7.3 [4+2] Additions; 2.8 Polymerizations; 2.9 Conclusions and Outlook; References; Chapter 3 Cooperating Ligands in Catalysis; 3.1 Introduction; 3.2 Chemically Active Ligands Assisting a Metal-Localized Catalytic Reaction

3.2.1 Cooperating Ligands with a Pendant Basic Site3.2.1.1 Functional Sites Located in the First Coordination Sphere of a Metal Complex; 3.2.1.2 Basic Functional Sites Located in the Outer Coordination Sphere; 3.2.2 Remote Pendant Basic Sites and Reorganization of π Systems as Driving Forces for Metal-Ligand Cooperativity; 3.2.3 Metal-Ligand Cooperation with a Pendant Acid Site; 3.3 Redox-Active Ligands Assisting Metal-Based Catalysts; 3.3.1 Redox-Active Ligands as Electron Reservoirs; 3.3.2 Redox-Active Ligands Participating in Direct Substrate Activation; 3.4 Summary; References

Chapter 4 Cooperative Enamine-Lewis Acid Catalysis4.1 Introduction; 4.1.1 Challenge in Combining Enamine Catalysis with Lewis Acid Catalysis; 4.2 Reactions Developed through Cooperative Enamine-Lewis Acid Catalysis; 4.2.1 α-Alkylation of Carbonyl Compounds; 4.2.1.1 α-Allylation of Aldehydes and Ketones; 4.2.1.2 α-Propargylation of Aldehydes; 4.2.1.3 α-Alkenylation and α-Arylation of Aldehydes; 4.2.1.4 α-Trifluoromethylation of Aldehydes Through Enamine Addition to Togni's Reagent; 4.2.2 Asymmetric Direct Aldol Reactions

4.2.2.1 Asymmetric Direct Aldol Reactions Catalyzed by Bifunctional Amine-Boronic Acid Catalysts

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (ebrary, viewed February 12, 2015).

ISBN:

9783527681044

3527681043

9783527681020

3527681027

9783527681051

3527681051

OCLC:

902675791