The genealogy of a gene : patents, HIV/AIDS, and race / Myles W. Jackson.

Format:

Book

Author/Creator:

Jackson, Myles W., author.

Series:

Transformations (M.I.T. Press).

Transformations: studies in the history of science and technology

Language:

English

Subjects (All):

Genes.

Genes--Patents.

Genetic genealogy.

HIV (Viruses).

Human population genetics.

Physical Description:

1 online resource (xii, 336 pages) : illustrations (black and white).

Place of Publication:

Cambridge, Massachusetts : The MIT Press, [2015]

Language Note:

English

Summary:

In The Genealogy of a Gene, Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied "genealogy" of CCR5 -- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics -- Jackson links a myriad of diverse topics. The history of CCR5 from the 1990s to the present offers a vivid illustration of how intellectual property law has changed the conduct and content of scientific knowledge, and the social, political, and ethical implications of such a transformation. The CCR5 gene began as a small sequence of DNA, became a patented product of a corporation, and then, when it was found to be an AIDS virus co-receptor with a key role in the immune system, it became part of the biomedical research world -- and a potential moneymaker for the pharmaceutical industry. When it was further discovered that a mutation of the gene found in certain populations conferred near-immunity to the AIDS virus, questions about race and genetics arose. Jackson describes these developments in the context of larger issues, including the rise of "biocapitalism," the patentability of products of nature, the difference between U.S. and European patenting approaches, and the relevance of race and ethnicity to medical research.

Contents:

The CCR5 story

The CCR5 patent(s)

Gene patenting and the product-of-nature doctrine

CCR5 and intellectual property law

The European response to the CCR5 patent

CCR5 and HIV/AIDS diagnostics and therapeutics

Race, place, and pathogens

Race, difference, and genes

Epilogue: the end of an error?

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographical references and index.

OCLC-licensed vendor bibliographic record.

ISBN:

0-262-32720-1

0-262-53378-2

0-262-32719-8

OCLC:

904398377