Cardiotoxicity of non-cardiovascular drugs / editor, Giorgio Minotti.

Format:

Book

Contributor:

Minotti, Giorgio.

Language:

English

Subjects (All):

Cardiovascular toxicology.

Physical Description:

1 online resource (362 p.)

Edition:

1st ed.

Place of Publication:

Chichester, West Sussex : Wiley, 2010.

Language Note:

English

Summary:

"First book to deal with this important area of adverse drug reactions -- cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals. Covers four important therapeutic classes: psychoactive drugs; anticancer drugs; non-steroidal anti-inflammatory drugs; and anti-retroviral drugs. - Emphasis on the preclinical screening of drug cardiotoxicity, to enable drug developers to test for this toxicity before starting expensive clinical trials"--Provided by publisher.

Contents:

Machine generated contents note: List of Contributors

1. Mitochondrial Dysfunction In Cell Injury and Cardiotoxicity

Fabio Di Lisa, Martina Semenzato, Andrea Carpi, Sara Menazza, Nina Kaludercic, Roberta Menabò, Marcella Canton

2. Cardiovascular Liabilities of Drugs: Regulatory Aspects

Claudio Arrigoni

3. Cellular Mechanisms, Molecular Targets, and Structure-Function Relationships In Drug-Induced Arrhythmias: The Case Of Antihistamines, Psychoactive Drugs, and Antimicrobial Agents

Maria Virginia Soldovieri and Maurizio Taglialatela

4. Cardiovascular Toxicity of Antitumor Drugs: Dimensions of the Problem in Children

Rebecca Scully, Louis Pruitt, Steven E. Lipshultz

5. Cardiovascular Toxicity of Antitumor Drugs: Dimension of the Problem in Adult Settings

Joseph R. Carver and Chaitali J. Desai

6. Diagnostic Aspects of Cardiovascular Toxicity of Antitumor Drugs

Michael S. Ewer, Thomas M. Suter

7. Cardiovascular Toxicity of Antitumor Drugs: Translating Molecular Mechanisms into Clinical Facts

Pierantonio Menna, Emanuela Salvatorelli, Carlo Salsano, Luca Gianni*, and Giorgio Minotti

8. NSAID Action and the Foundations for Cardiovascular Toxicity

Anna L. Blobaum and Lawrence J. Marnett

9. Cardiovascular toxicities of NSAIDS: Epidemiologic aspects

Antonio González-Pe;rez, Luis Alberto Garci;a Rodriguez

10. Cardiovascular Toxicities of Life-Saving Drugs: Antiviral Therapy

James J. Kohler & William Lewis.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on metadata supplied by the publisher and other sources.

ISBN:

9786612548048

9781282548046

1282548042

9780470660379

0470660376

9780470660386

0470660384

OCLC:

612432607