Neuroinflammation and CNS disorders / edited by Nicola Woodroofe, Sandra Amor.

Format:

Book

Contributor:

Woodroofe, Nicola, editor.

Amor, Sandra, editor.

Language:

English

Subjects (All):

Inflammation--Pathophysiology.

Inflammation.

Central nervous system--Diseases--Immunological aspects.

Central nervous system.

Nervous system--Degeneration--Immunological aspects.

Nervous system.

Physical Description:

1 online resource (420 p.)

Edition:

First edition.

Place of Publication:

West Sussex, England : John Wiley & Sons, 2014.

Language Note:

English

Summary:

The last decade has seen an upsurge of information on the role of immune responses in neurodegenerative disorders. In many of these diseases it is still unclear whether the innate and adaptive responses are pathogenic or play a role in repair, and thus understanding their precise roles is key to controlling these diseases by designing immune-therapeutic approaches. The connection between many neurological diseases is the realisation that the immune and nervous systems are inextricable linked, and that perturbations in this delicate balance are involved in many disorders. This has open

Contents:

Immune privilege of the brain

Innate immunity in the CNS : a focus on the myeloid cell

Adaptive immune responses in the CNS

Ageing and the immune response in the CNS

Brain repair : the role of endogenous and transplanted neural stem cells

Neuroinflammation in Alzheimer's, Parkinson's, and Huntington's diseases

CNS infections

Neuroimmunology of amyotrophic lateral sclerosis

Demyelinating disorders of the CNS

Other autoimmune disorders : systemic lupus erythematosus, primary Sjogren's syndrome, gluten-related neurological dysfunction, and paraneoplastic neurological syndromes

Inflammation in the pathogenesis of depression

Immune responses in the CNS in epilepsy

Inflammatory mediators and dysfunction of the neurovascular unit following ischaemia reperfusion

Spinal cord injury

Immune responses to tumours in the CNS.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

9781118406540

1118406540

9781118406557

1118406559

9781118406533

1118406532

OCLC:

880451431