Dystonia 4 / editors, Stanley Fahn, Mark Hallett, Mahlon R. DeLong ; acquisitions editor, Anne M. Sydor ; developmental editor, Alyson Forbes ; production editor, Emmeline Parker ; manufacturing manager, Benjamin Rivera ; cover designer, Patricia Gast.

Format:

Book

Author/Creator:

International Dystonia Symposium, Corporate Author.

Contributor:

Fahn, Stanley, 1933-

Hallett, Mark.

DeLong, Mahlon R.

Sydor, Anne M.

Forbes, Alyson.

Parker, Emmeline.

Rivera, Benjamin.

Gast, Patricia.

Dystonia Medical Research Foundation.

National Institutes of Health (U.S.)

Series:

Advances in neurology ; v. 94.

Advances in Neurology, 0091-3952 ; Volume 94

Language:

English

Subjects (All):

Dystonia--Congresses.

Dystonia.

Physical Description:

1 online resource (368 pages) : illustrations, graphs.

Edition:

1st ed.

Place of Publication:

Philadelphia, Pennsylvania : Lippincott Williams & Wilkins, 2004.

Language Note:

English

Summary:

Written by leading international experts in all relevant clinical and basic science disciplines, Dystonia 4 is a state-of-the-art review of recent progress in the understanding and treatment of the dystonias. It provides a comprehensive update on the many breakthroughs that have occurred in the five years since the highly acclaimed Dystonia 3 was published. The therapeutics section features detailed discussions on botulinum toxin treatment and current surgical procedures. The book also includes a major section on recent advances in understanding the genetics of the dystonias. Other sections focus on pathophysiology, Oppenheim's dystonia, PET and biochemical studies, and musician's and other focal dystonias.

Contents:

Intro

Contents

Contributing Authors

Preface

Acknowledgments

I: Pathophysiology

1 Dystonia: Abnormal Movements Result from Loss of Inhibition

2 Sensory Deficits in Dystonia and Their Significance

3 Focal Hand Dystonia May Result from Aberrant Neuroplasticity

4 Basal Ganglia Neuronal Discharge in Primary and Secondary Dystonia

5 Evidence of Widespread Impairment of Motor Cortical Inhibition in Focal Dystonia: A Transcranial Magnetic Stimulation Study in

6 Modulation of Cortical Activity by Repetitive Transcranial Magnetic Stimulation (rTMS): A Review of Functional Imaging Studies

II: Oppenheim's Dystonia

7 Dopamine Transmission in DYT1 Dystonia

8 Development and Anatomic Localization of TorsinA

9 Mouse Models of TorsinA Dysfunction

10 Dominant TorsinA Mutations in Cellular Systems

11 An Animal Model to Discern Torsin Function: Suppression of Protein Aggregation in

12 TorsinA and Early-Onset Torsion Dystonia

13 An Epidemiologic Survey of Dystonia Within the Entire Population of Northeast England Over the Past Nine Years

III: Other Genetic Disorders

14 Dystonia Genotypes, Phenotypes, and Classification

15 Update on the Genetics of Primary Torsion Dystonia Loci

and

and the Dystonia-Plus Locus

16 Inherited Myoclonus-Dystonia

17 Penetrance and Expression of Dystonia Genes

18 Update on Dopa-Responsive Dystonia: Locus Heterogeneity and Biochemical Features

19 X-Linked Recessive Dystonia Parkinsonism (XDP

Lubag

DYT3)

20 Focal Dystonia Is Associated with a Polymorphism of the Dopamine D5 Receptor Gene

21 Dystonia With and Without Deafness Is Caused by TIMM8A Mutation

IV: PET and Biochemistry of Dystonia

22 Abnormal Brain Networks in Primary Torsion Dystonia

23 Dysfunction of Dopaminergic Pathways in Dystonia.

24 Clinical Presentation and Progression of Sporadic and Familial Primary Torsion Dystonia in Italy

25 Cognition and Affect in Patients with Cervical Dystonia With and Without Tremor

26 Clinical Features of the

in Cervical Dystonia

27 Executive Function in Dystonia

28 Duration of Effectiveness of Botulinum Toxin Type B in the Treatment of Cervical Dystonia

29 Is Phenotypic Variation of Hereditary Progressive Dystonia with Marked Diurnal Fluctuation/Dopa-Responsive Dystonia (HPD/DRD)

V: Musicians' and Other Focal Dystonias

30 Focal Task-Specific Dystonia in Musicians

31 Brain Mapping in Musicians with Focal TaskSpecific Dystonia

32 Three-Dimensional Movement Analysis as a Promising Tool for Treatment Evaluation of Musicians' Dystonia

33 Limb Immobilization for Occupational Dystonia: A Possible Alternative Treatment for Selected Patients

34 Review of 113 Musicians with Focal Dystonia Seen Between 1985 and 2002 at a Clinic for Performing Artists

35 The Impact of Focal Dystonia on the Working Life of Musicians in the United Kingdom

36 Long-Term Outcome of Focal Dystonia in Instrumental Musicians

37 Abnormal Sensorimotor Processing in Pianists with Focal Dystonia

VI: Therapeutics

38 Dystonia: Medical Therapy and Botulinum Toxin

39 Pallidotomy for Generalized Dystonia

40 Pallidal Stimulation for Dystonia

41 Off-Period Dystonia in Parkinson's Disease but Not Generalized Dystonia Is Improved By High-Frequency Stimulation of the Subt

42 Autonomic Side Effects of Botulinum Toxin Type B Therapy

43 Dystonia and Headaches: Clinical Features and Response to Botulinum Toxin Therapy

44 Rating Scales for Dystonia: Assessment of Reliability of Three Scales

Subject Index.

Notes:

"Fourth International Dystonia Symposium, sponsored by the Dystonia Medical Research Foundation and the National Institutes of Health, was held in Atlanta, Georgia, on June 13-15, 2002"--Preface.

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (ebrary, viewed January 23, 2014).

ISBN:

1-4698-7731-7

OCLC:

908076205