Evidence-based management of lipid disorders / Maud N. Vissers, John J.P. Kastelein, Erik S. Stroes, [editors].

Format:

Book

Author/Creator:

Vissers, Maud N.

Contributor:

Vissers, Maud N.

Kastelein, John J. P.

Stroes, Erik S.

Language:

English

Subjects (All):

Lipids--Metabolism--Disorders--Treatment.

Lipids.

Evidence-based medicine.

Physical Description:

1 online resource (322 p.)

Edition:

1st ed.

Place of Publication:

Harley : TFM, 2010.

Language Note:

English

Summary:

Practising evidence-based medicine necessarily depends on the clinician having access to the best evidence available, but in a fast-moving field, keeping up to date with the latest developments is a challenging prospect. In this new volume, leading experts focus on the most important clinical issues associated with the management of lipid disorders, evaluating and interpreting the evidence available to provide the reader with a reliable summary of our current knowledge. Topics covered include therapeutical strategies for managing hereditary lipid disorders, including familial hypercholesterolemia, both in adults and children, and familial combined hypercholesterolemia. The authors also evaluate the evidence for a link between inflammatory disease and cardiovascular risk; the metabolic syndrome and the interconnections between dyslipidemias and diabetes. They also look at therapeutic challenges such as the management of patients who are statin resistant, and the control of lipid levels in those suffering renal insufficiency. Tables highlight important data, evidence from trial results and expert reports, and each section concludes with a series of key points that present a summary of evidence-based recommendations for best practice, graded according to the quality of that evidence. Evidence-based Management of Lipid Disorders provides the busy clinician with a unique analysis of the data supporting current therapies and will help the reader formulate effective strategies for treating their own patients.

Contents:

""COVER FRONT""; ""Contents""; ""Foreword""; ""Contributors""; ""Acknowledgements""; ""Using evidence-based medicine""; ""Chapter 1 How much evidence is enough?""; ""Chapter 2 A brief review of lipoprotein metabolism""; ""Chapter 3 Epidemiological aspects of lipid and lipoprotein levels in relation to cardiovascular diseases""; ""Chapter 4 Are LDL cholesterol-lowering functional food ingredients successful in the long term?""; ""Chapter 5 Evidence-based treatment of primary hypo- and hypercholesterolemic disorders""; ""Chapter 6 Does raising HDL protect against atherosclerosis?""

""Chapter 7 How do we diagnose hypertriglyceridemia in clinical practice and what are the consequences for treatment?""""Chapter 8 The optimal treatment of patients with familial combined hyperlipidemia""; ""Chapter 9 How to manage lipid and lipoprotein disorders in children""; ""Chapter 10 Contribution of the atherogenic dyslipidemic phenotype to the increased cardiovascular disease risk of the metabolic syndrome and diabetes mellitus""; ""Chapter 11 What are the consequences of renal insufficiency or the nephrotic syndrome for lipid levels?""

""Chapter 12 The link between chronic inflammatory diseases and cardiovascular risk""""Chapter 13 What is the evidence for a physiological and pathogenic role of lipoprotein (a)?""; ""Chapter 14 Sitosterolemia; xenophobia for the body""; ""Chapter 15 How can we deal with inborn errors in cholesterol and bile acid biosynthesis?""; ""Chapter 16 Differential diagnosis of patients with xanthomas and xanthelasmata""; ""Chapter 17 When should we fear statin interactions?""; ""Chapter 18 What are the considerations in patients who are statin �intolerant�?""; ""Index""; ""COVER BACK""

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-908986-59-X

OCLC:

923424667