MicroRNAs in medicine / edited by Charles H. Lawrie.

Format:

Book

Contributor:

Lawrie, Charles H.

Language:

English

Subjects (All):

RNA.

Genetic regulation.

Physical Description:

1 online resource (722 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, New Jersey : Wiley, [2014]

Language Note:

English

Summary:

"MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions of the latest microRNA research written by international leaders in their field. Opening with an introduction to what microRNAs are and how they function, the book goes on to explore the role of microRNAs in normal physiological functions, infectious diseases, non-infectious diseases, cancer, circulating microRNAs as non-invasive biomarkers, and finally their potential as novel therapeutics.Including background information on the field as well as reviews of the latest research breakthroughs, MicroRNAs in Medicine is a one-stop source of information to satisfy the specialists and non-specialists alike, appealing to students, researchers, and clinicians interested in understanding the potential of microRNAs in medicine and research"--Provided by publisher.

Contents:

Chapter 1. MicroRNAs : a brief introduction / Prof. Charles H. Lawrie. Section I: MicroRNAs as physiological regulators. Chapter 2. MicroRNA regulation of stem cell fate and reprogramming / Dr Erica Vivas, Dr Gustavo Tiscornia & Prof. Juan Carlos Izpisua Belmonte

Chapter 3. MicroRNAs as regulators of immunity / Dr. Donald Gracias & Prof. Peter D. Katsikis

Chapter 4. Regulation of senescence by microRNAs / Dr Ioannis Grammatikakis & Dr Myriam Gorospe

Chapter 5. The emergence of geroMIRS: A group of microRNAs implicated in aging / Dr Alejandro Ugalde, Dr Agnieszka Kwarciak, Dr Xurde Caravia, Prof. Carlos Lopez-Ot¡n & Dr Andrew Ramsay

Chapter 6. MicroRNAs and hematopoiesis / Dr Sukhinder Sandhu & Prof. Ramiro Garzon

Chapter 7. MicroRNAs in platelet production and activation / Dr Leonard Edelstein, Dr Srikanth Nagalla & Prof. Paul Bray

Section II: MicroRNAs in infectious disease: host-pathogen interactions. Chapter 8. MicroRNAs as key players in host-virus interactions / Dr Aur¿lie Fender & Dr S¿bastien Pfeffer

Chapter 9. MicroRNA expression in avian herpesviruses / Dr. Yongxiu Yao & Prof. Venugopal Nair

Chapter 10. Function of human cytomegalovirus microRNAs and potential roles in latency / Dr Natalie Reynolds, Dr Jon Pavelin & Dr Finn Grey

Chapter 11. Involvement of small non-coding RNA in HIV-1 infection / Dr Guihua Sun, Prof. John Rossi & Dr Daniela Castanotto

Chapter 12. MicroRNA in malaria / Dr Panote Prapansilp & Prof. Gareth Turner

Section III: Cancer. Chapter 13. The microRNA decalog of cancer involvement / Dr Tanja Kunej, Dr Irena Godnic, Dr Minja Zorc, Dr Simon Horvat & Prof. George Calin

Chapter 14. MicroRNAs as oncogenes and tumor suppressors / Dr Eva Rufino-Palomares, Dr Fernando Reyes-Zurita, Dr Jose Lupiez & Dr Pedro Medina

Chapter 15. Long non-coding RNAs and their roles in cancer / Dr Yolanda Sanchez & Dr Maite Huarte

Chapter 16. Regulation of hypoxia responses by microRNA expression / Dr Carme Camps, Prof. Adrian Harris & Dr Jiannis Ragoussis

Chapter 17. Control of receptor function by microRNAs in breast cancer / Dr Claudia Piovan & Dr Marilena Iorio

Chapter 18. MicroRNAs in human prostate cancer : from pathogenesis to therapeutic implications / Dr. Mustafa Ozen & Dr Omer Karatas

Chapter 19. MicroRNA signatures as biomarkers of colorectal cancer / Dr Katrin Pfitze, Dr Xiaoya Luo & Prof. Barbara Burwinkel

Chapter 20. Genetic variations in microRNA-encoding sequences and microRNA target sites alter lung cancer susceptibility and survival / Dr Min Yang & Prof. Dongxin Lin

Chapter 21. MicroRNAs in myelopoiesis and myeloid disorders / Dr Sara Meyer & Prof. Lee Grimes

Chapter 22. MicroRNA deregulation by aberrant DNA methylation in acute lymphoblastic leukemia / Dr Xabier Agirre & Dr Felipe Prosper

Chapter 23. Role of miRNAs in the pathogenesis of chronic lymphocytic leukemia / Dr Veronica Balatti, Prof. Yuri Pekarky, Dr Lara Rizzotto & Prof. Carlo Croce

Chapter 24. MicroRNA in B-cell non-Hodgkin lymphoma: Diagnostic markers and therapeutic targets / Dr Nerea Mart¡nez, Dr Lorena Di Lisio & Prof. Miguel Piris

Chapter 25. MicroRNAs in diffuse large B-cell lymphoma / Prof. Izidore Lossos & Dr Alvaro Alencar

Chapter 26. The role of microRNAs in Hodgkin lymphoma / Dr. Wouter Plattel, Dr. Joost Kluiver, Dr Arjan Diepstra, Dr Lydia Visser & Prof. Anke van den Berg

Chapter 27. MicroRNA expression in cutaneous T-cell lymphomas / Prof. Cornelis Tensen

Section IV: Hereditary and other non-infectious diseases. Chapter 28. MicroRNAs and hereditary disorders / Dr Matias Morin and Prof. Miguel Moreno-Pelayo

Chapter 29. MicroRNAs and cardiovascular diseases / Prof. Koh Ono

Chapter 30. MicroRNAs and diabetes / Prof. Ramono Regazzi

Chapter 31. MicroRNAs in liver disease / Dr Patricia Munoz-Garrido, Dr Marco Marzioni, Dr Elizabeth Hijona, Dr Luis Bujanda & Dr Jesus Banales

Chapter 32. MicroRNA regulation in multiple sclerosis / Dr Andreas Junker

Chapter 33. The role of microRNAs in Alzheimer's disease / Dr Shahar Barbash & Prof. Hermona Soreq

Chapter 34. Current views on the role microRNAs in psychosis / Dr Aoife Kearney, Dr Javier Bravo & Prof. Timothy Dinan. Section V: Circulating microRNAs as cellular messengers and novel biomarkers. Chapter 35. Circulating microRNAs as non-invasive biomarkers / Ass. Prof. Heidi Schwarzenbach & Prof. Klaus Pantel

Chapter 36. Circulating microRNAs as cellular messengers / Prof. Kasey Vickers

Chapter 37. Release of microRNA-containing vesicles can stimulate angiogenesis and metastasis in renal carcinoma / Dr Federica Collino, Dr Cristina Grange & Prof. Giovanni Camussi

Section VI: Therapeutic uses of microRNAs: Current perspectives and future directions. Chapter 38. MicroRNA regulation of cancer stem cells and microRNAs as potential cancer stem cell therapeutics / Dr Can Liu & Prof. Dean Tang

Chapter 39. Therapeutic modulation of microRNAs / Prof. Achim Aigner & Dr Hannelore Dassow

Chapter 40. Silencing of MicroRNA-122 in primates with chronic hepatitis C virus infection / Dr Henrik Orum.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on online resource; title from PDF title page (ebrary, viewed December 9, 2013).

ISBN:

9781118300343

1118300343

9781118300312

1118300319

9781118300411

1118300416

OCLC:

858914538