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Structure-activity relationship studies in drug development by NMR spectroscopy. [Volume 1] / editors, Atta-ur-Rahman, M. Iqbal Choudhary.
- Format:
- Book
- Author/Creator:
- Rahman, Atta-ur, Author.
- Series:
- Structure-activity relationship studies in drug development by NMR spectroscopy, 2210-2701 ; v. 1
- Language:
- English
- Subjects (All):
- Nuclear magnetic resonance spectroscopy.
- Drugs--Design.
- Drugs.
- Physical Description:
- 1 online resource (221 p.)
- Edition:
- 1st ed.
- Place of Publication:
- [Saif Zone, Sharjah, United Arab Emirates] : Bentham Science Publishers Ltd., [2011]
- Language Note:
- English
- Summary:
- NMR (Nuclear Magnetic Resonance) Spectroscopy has found significant applications in drug discovery based on its capacity to map molecular interactions at the atomic level. Chemical shifts, cross relaxation, and exchange of protons are among the NMR parameters which are highly sensitive to the exact environment of the molecules, and therefore yield information about whether a small molecule (candidate compound) binds to a target protein (receptor) or to other macromolecules. These NMR parameters are also used to exactly map the part of the macromolecular target to which the ligand is bound. Spe
- Contents:
- Cover; eBooks End User License Agreement; Contents; PREFACE; Contributors; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Chapter 06; Chapter 07; Author Index
- Notes:
- Cover title.
- Includes bibliographical references and index.
- ISBN:
- 9781608051649
- 1608051641
- OCLC:
- 795119919
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