Quinones : occurrence, medicinal uses and physiological importance / Ervin R. Price and Smith C. Johnson, editors.

Format:

Book

Contributor:

Price, Ervin R.

Johnson, Smith C.

Series:

Biochemistry research trends series.

Biochemistry research trends

Language:

English

Subjects (All):

Quinone.

Physical Description:

1 online resource (194 p.)

Edition:

1st ed.

Place of Publication:

Hauppauge, N.Y. : Nova Science Publishers, Inc., 2013.

Language Note:

English

Summary:

In this book, the authors present current research in the study of the occurrence, medicinal uses and physiological importance of quinones. Topics discussed in this compilation include the biological implications of benzoquinones; dihydropyrimidinone derivates and their redox reactivity and pharmacological relevance; quinone monoacetal compounds in the application of controlled reactions with nucleophiles; quinone oxidoreductase 2 in the brain and retina; and plasma membrane CoQ, porin, and redox control of autism.

Contents:

Intro

QUINONES: OCCURRENCE,MEDICINAL USES AND PHYSIOLOGICAL IMPORTANCE

QUINONES: OCCURRENCE, MEDICINAL USES AND PHYSIOLOGICAL IMPORTANCE

Library of Congress Cataloging-in-Publication Data

CONTENTS

PREFACE

Chapter 1: DIHYDROPYRIMIDINONE DERIVATIVES: REDOX REACTIVITY, PHARMACOLOGICAL RELEVANCE AND MEDICINAL APPLICATIONS

ABSTRACT

INTRODUCTION

1. OXIDATIONS

2. REDUCTION

3. BIOLOGICAL ACTIVITY

REFERENCES

Chapter 2: BIOLOGICAL IMPLICATIONS OF BENZOQUINONES

1. ENDOGENOUSLY OCCURRING BENZOQUINONES

2. EXOGENOUSLY OCCURRING BENZOQUINONES

CONCLUSION

Chapter 3: QUINONE MONOACETAL COMPOUNDS IN APPLICATION TO CONTROLLED REACTIONS WITH NUCLEOPHILES

1. EFFICIENT PREPARATION OF QUINONE MONOACETALS

2. GENERAL GUIDELINES FOR THE REACTIVITIES OF QUINONE MONOACETALS TOWARD NUCLEOPHILES

3. INTRAMOLECULAR REACTIONS FOR THE SYNTHESIS OF NATURAL PRODUCTS

Chapter 4: CATECHOLQUINONES AS SUBSTRATES OF THE NRH: QUINONE OXIDOREDUCTASE 2 IN THE BRAIN AND RETINA

1. INTRODUCTION

2. CATECHOL QUINONES

3. NQO2 REDUCING CATHECHOL QUINONES

Chapter 5: PLASMA MEMBRANE COQ, PORIN, AND REDOX CONTROL OF AUTISM

THE SENTINELS OF PLASMA MEMBRANE REDOX CONTROL

REQUIREMENT OF Q IN PM MEDIATED REDUCTION OF FECN6

PLASMA MEMBRANE COENZYME Q IS REQUIRED FOR FULL REDOX FUNCTION OF VDAC

COQ10 IS REQUIRED FOR NADH-FERRICYANIDE REDUCTION IN DIVERSE SPECIES

VDAC AND REDOX CONTROL OF PORIN IN AUTISM

CONCLUDING REMARKS

METHODS

ACKNOWLEDGMENTS

INDEX.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-62618-324-4

OCLC:

923667964