1 option
Glia and inflammation in neurodegenerative disease
- Format:
- Book
- Author/Creator:
- Yenari, M. A.
- Series:
- Nova biomedical Glia and inflammation in neurodegenerative disease
- Language:
- English
- Subjects (All):
- Nervous system--Degeneration.
- Nervous system.
- Inflammation.
- Nervous System Diseases.
- Cells.
- Pathologic Processes.
- Nervous System.
- Medicine.
- Pathological Conditions, Signs and Symptoms.
- Anatomy.
- Health Occupations.
- Disease.
- Occupations.
- Neuroglia.
- Neurodegenerative Diseases.
- Pathology.
- Medical Subjects:
- Nervous System Diseases.
- Cells.
- Pathologic Processes.
- Nervous System.
- Medicine.
- Pathological Conditions, Signs and Symptoms.
- Anatomy.
- Health Occupations.
- Disease.
- Occupations.
- Neuroglia.
- Inflammation.
- Neurodegenerative Diseases.
- Pathology.
- Physical Description:
- 1 online resource (283 pages)
- Edition:
- 1st ed.
- Place of Publication:
- [Place of publication not identified] Nova Science 2006
- Language Note:
- English
- Summary:
- The brain has long been considered an immune privileged organ, meaning that inflammatory cells are excluded due to a relatively impenetrable blood brain barrier (BBB). However, this is not to say that the central nervous system is incapable of eliciting immune responses, as resident inflammatory cells exist within the brain parenchyma. Microglia have long been thought to be the brain's resident immune cell with myeloid lineage similar to monocytes and macrophages. In this volume, the authors review the current state of knowledge with regard to immune responses and cell-cell interactions as they pertain to a variety of neurodegenerative diseases. The changing role of inflammation with development is considered. They also present a summary of the various therapeutic strategies employed both in the laboratory and at the clinical level.
- Contents:
- Role of microglia in CNS inflammation / Wolfgang J. Streit ... [et al.]
- Astrocytes as inflammatory cells in acute and chronic neurodegeneration / Valerie Chock and Rona Giffard
- Cell death pathways and the immune response / Jennifer M. Pocock ... [et al.]
- Glial-neuronal cross-talk in neurodegeneration / Michael P. Flavin
- Inflammation in stroke / Xian Nan Tang and Midori A. Yenari
- Inflammatory processes in Alzheimer's disease / Michael T. Heneka
- Neuroinflammation and Parkinson's disease / R. Lee Mosley ... [et al.,]
- Inflammation and ischemia in the developing brain / Zinaida S. Vexler.
- Notes:
- Bibliographic Level Mode of Issuance: Monograph
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.