Antimicrobial peptides : properties, functions and role in immune response / Myung-Dae Seong and Young-Il Hak, editors.

Format:

Book

Contributor:

Seong, Myung-Dae.

Hak, Young-Il.

Series:

Immunology and immune system disorders.

Cell biology research progress.

Immunology and immune system disorders

Cell biology research progress

Language:

English

Subjects (All):

Peptide antibiotics.

Physical Description:

1 online resource (180 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Biomedical, 2013.

Language Note:

English

Summary:

Antimicrobial peptides (AMPs) are small peptides which exhibit broad-spectrum antimicrobial activity and often activity against virus. In addition, AMPs exert several functions including endotoxin neutralization, chemotactic and immunomodulating activities, angiogenesis, and wound repair. In this book, the authors discuss the innate immune system and lipopolysaccharides; the biological role of fish antimicrobial peptides; casein-derived peptides; antimicrobial peptides in intestinal inflammation and infection; insect antimicrobial peptides in immunity and mechanisms of action; potential of AMPs as therapeutic tools against infectious disease; and how LC-MS/MS-based quantitative protein profiling can aid mechanistic studies of antimicrobial peptides.

Contents:

Intro

ANTIMICROBIAL PEPTIDES: PROPERTIES, FUNCTIONS AND ROLE IN IMMUNE RESPONSE

LIBRARY OF CONGRESS CATALOGING-IN-PUBLICATION DATA

CONTENTS

PREFACE

Chapter 1: Modification in Lipopolysaccharide That Reduce Interaction of Bacterial Pathogens with the Innate Immune System and Cause Resistance to Antimicrobial Peptides

ABSTRACT

THE INNATE IMMUNE SYSTEM AND THE LIPOPOLYSACCHARIDE

SALMONELLA ENDOTOXIN, THE "CANONICAL" LPS

PROTEUS MIRABILIS

YERSINIA

BRUCELLA

BORDETELLA

CONCLUSION

REFERENCES

Chapter 2: Biological Role of FIsh Antimicrobial Peptides

1. INTRODUCTION

2. GENERAL STRUCTURE, CLASSIFICATION AND WAY OF ACTION

3. BIOLOGICAL ROLE OF AMPS IN FISH

ACKNOWLEDGMENTS

Chapter 3: Casein-Derived Peptides

INTRODUCTION

PROPERTIES

FUNCTION

Chapter 4: Antimicrobial Peptides in Intestinal Inflammation and Infection

NATURAL ANTIMICROBIAL PEPTIDE CATEGORY

NATURAL ANTIMICROBIAL PROTEIN CATEGORY

NOVEL OR ARTIFICIAL ANTIMICROBIAL PEPTIDE CATEGORY

MODIFIED CATHELICIDIN CATEGORY

Chapter 5: Antimicrobial Peptides: Immunimodulatory Properties, Functions and Therapeutic Applications in Humans

HISTORICAL OUTLINE AND CLASSIFICATION

AMPS PROPERTIES, EXPRESSION AND REGULATION

FUNCTIONS OF AMPS

AMPS ROLE IN IMMUNE RESPONSES AND INFLAMMATORY DISEASES

AMPS AS THERAPEUTIC TOOLS

Chapter 6: The Role of Insect Antimicrobial Peptides in Immunity and Mechanisms of Action

INSECT IMMUNITY

CLASSIFICATION OF INSECT AMPS

INSECT AMPS

REFERENCES.

Chapter 7: Potential of AMPs as Therapeutic Tools Against Infectious

EFFICIENCY

IN VIVO STABILITY AND TOXICITY

COST OF MANUFACTURING

ACQUISITION OF RESISTANCE

Chapter 8: LC-MS/MS-Based Quantitative Protein Profiling Can Aid Mechanistic Studies of Antimicrobial Peptides

ANTIMICROBIAL PEPTIDES: EXCELLENT CANDIDATES FOR DEVELOPMENT AS NOVEL ANTIMICROBIAL DRUGS

QUANTITATIVE PROTEIN PROFILING CAN AID MECHANISTIC STUDIES OF AMPS

Index.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-62257-844-9

OCLC:

858980756