1 option
Progress in neurodegeneration : the role of metals / Maria Rosa Avila-Costa and Veronica Anaya Martinez, editors.
- Format:
- Book
- Author/Creator:
- Avila-Costa, Maria Rosa.
- Series:
- Neurodegenerative diseases--laboratory and clinical research series.
- Neurodegenerative diseases--laboratory and clinical research series
- Language:
- English
- Subjects (All):
- Nervous system--Degeneration.
- Nervous system.
- Metals--Toxicology.
- Metals.
- Neurotoxicology.
- Physical Description:
- 1 online resource (398 p.)
- Edition:
- 1st ed.
- Place of Publication:
- New York : Nova Science Publishers, c2009.
- Language Note:
- English
- Summary:
- This book highlights the role of some metals which induce oxidative stress and imbalances in the neurodegenerative diseases such as Alzheimer disease, Parkinson disease, Amyotrophic Lateral Sclerosis, Huntington Disease, and other dementias. The chemistry and biochemistry of metals induced-oxidative stress, protein damage is first described, followed by the evidence for a pathological role of oxidative stress in these disease states. It is tempting to speculate that free radical oxygen chemistry contributes to pathogenesis in all these conditions, though it is as yet undetermined what types of oxidative changes occur early in the disease, and what types are secondary manifestations of neuronal degeneration. Finally the authors review different metals to describe their specific role in the different pathologies.
- Contents:
- The nervous system and brain damage / Maria Rosa Avila-Costa ... [et al.]
- Neurodegenerative diseases / Maria Rosa Avila-Costa, Leonardo Reynoso Erazo, Jose Luis Ordoñez Librado
- Metals, toxicity and neurodegeneration / Maria Rosa Avila-Costa ... [et al.]
- Aluminum / Maria Rosa Avila-Costa ... [et al.]
- Manganese / Jose Luis Ordoñez-Librado
- Cadmium / Jose Luis Ordoñez-Librado, Maria Rosa Avila-Costa
- Zinc / Ricardo García-Ruiz
- Vanadium / Maria Rosa Avila-Costa
- Lead / Ana Luisa Gutierrez-Valdez
- Iron / Enrique Montiel-Flores ... [et al.]
- Mercury / Maria Luisa Juárez-Seres, Ana Luisa Gutierrez Valdéz, Maria Rosa Avila-Costa
- Copper / Verónica Anaya-Martínez, Maria Rosa Avila-Costa.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- ISBN:
- 1-61728-570-6
- OCLC:
- 665795359
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.