Computational metabolomics / Nabil Semmar.

Format:

Book

Author/Creator:

Semmar, Nabil.

Series:

Metabolic diseases--laboratory and clinical research series.

Metabolic diseases--laboratory and clinical research

Language:

English

Subjects (All):

Metabolites.

Physical Description:

1 online resource (250 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, c2011.

Language Note:

English

Summary:

Metabolism represents a complex system characterised by a high variability in metabolites' structure, concentration and regulation ratio. Such variability is observed at different metabolic scales going from metabolites to metabolic profiles via chemical reactions and metabolic pathways, as well as under static or dynamic aspects. Variations in these components are due to apparition-disappearance, level increase-decrease and/or relative changes in weights or contributions leading to different structural, functional and evolutive states of the metabolic system. This book presents a variety of different computational approaches of the variability in metabolic systems.

Contents:

General classification of metabolomic approaches

Stoichiometry-based approaches

Correlation-based approaches

Distances- and similarity indices-based approaches : cluster analysis

Outliers and extreme cases analysis

Weighted metabolic profiles analysis

Time-dependent analysis of metabolic systems.

Notes:

Description based upon print version of record.

Includes bibliographical references (p. [213]-232) and index.

Description based on print version record and CIP data provided by publisher.

ISBN:

1-61324-267-0

OCLC:

738476063