Pharmacogenomics of human drug transporters : clinical impacts / edited by Toshihisa Ishikawa, Richard B. Kim, Jörg König.

Format:

Book

Contributor:

Ishikawa, Toshihisa.

Kim, Richard B.

König, Jörg.

Language:

English

Subjects (All):

Biological transport.

Drug interactions.

Pharmacogenetics.

Physical Description:

1 online resource (441 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, N.J. : Wiley, c2013.

Language Note:

English

Summary:

Sets the foundation for safer, more effective drug therapies With this book as their guide, readers will discover how to apply our current understanding of the pharmacogenomics of drug transporters to advance their own drug discovery and development efforts. In particular, the book explains how new findings in the field now enable researchers to more accurately predict drug interactions and adverse drug reactions. Moreover, it sets the foundation for the development of drug therapies that are tailored to an individual patient's genetics. Pharmacogenomics of Human Drug Tran

Contents:

Introduction to pharmacogenomics of drug transporters / Marianne K DeGorter and Richard B Kim

ADME pharmacogenomics in drug development / Liangfu Chen and Joseph W. Polli

Regulatory perspective on pharmacogenomics of drug metabolizing enzymes and transporters / Lei Zhang ... [et al.]

The pharmacogenomics of membrane transporters project / Sook Wah Yee, Deanna L. Kroetz, Kathleen M. Giacomini

Emerging new technology of SNP typing / Toshihisa Ishikawa and Yoshihide Hayashizaki

Chapters 6: OATP1A2, OAT1 and OAT3 / Rommel G. Tirona

OATP1B1, OATB1B3 and OATP2B1 / Jorg Konig and Martin Fromm

OCT (SLC22A) and OCTN families / Sophie L. Stocker ... [et al.]

MATE (SLC47) family / Atsushi Yonezawa and Ken-ichi Inui

PEPT (SLC15A) family / Tomoko Sugiura ... [et al.]

Nucleoside transporters (SLC28 and SLC29) family / Míriam Molina-Arcas

Maral pastor-anglada

P-glycoprotein (MDR1/ABCB1) / Ingolf Cascorbi

Bile salt export pump BSEP (ABCB11) : role in liver physiology and liver disease / Gerd Ullak-Kublick and Bruno Stieger

BCRP (ABCG2) / Agnes Basseville ... [et al.]

MRP2 (ABCC2) and MRP3 (ABCC3) / Anne T. Nies

MRP4 (ABCC4) / Satish B.Cheepala, Mugdha Sukthankar, John D. Schuetz

MRP8 (ABCC11) / Yu Toyoda, Toshihisa Ishikawa

Future perspectives / Toshihisa Ishikawa, Joseph Ware.

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from title page (ebrary, viewed May 9, 2013).

ISBN:

9781118353240

1118353242

9781118353257

1118353250

9781299385283

1299385281

9781118353202

111835320X

OCLC:

831117883