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Reverse genetics of RNA viruses : applications and perspectives / edited by Anne Bridgen.

Ebook Central Academic Complete Available online

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Format:
Book
Contributor:
Bridgen, Anne, 1961-
Language:
English
Subjects (All):
RNA viruses.
Reverse genetics.
Viral proteins.
Viral vaccines.
Physical Description:
1 online resource (414 p.)
Edition:
1st ed.
Place of Publication:
Chichester, West Sussex : John Wiley & Sons, 2013.
Language Note:
English
Summary:
Reverse genetics, the genetic manipulation of RNA viruses to create a wild-type or modified virus, has led to important advances in our understanding of viral gene function and interaction with host cells. Since many severe viral human and animal pathogens are RNA viruses, including those responsible for polio, measles, rotaviral diarrhoea and influenza infections, it is also an extremely powerful technique with important potential application for the prevention and control of a range of human and animal viral diseases. Reverse Genetics of RNA Viruses provides a comprehensive
Contents:
Definitions of reverse genetics, +ve, -ve, sense and doubled stranded (DS) RNA viruses / Anne Bridgen
Coronavirus reverse genetics / Paul Britton
Hepatitis C and use of reverse genetics in drug design / Natalia Frias Staheli
Norovirus reverse genetics / Ian Goodfellow
Rhabdovirus reverse genetics / Klaus Conzelmann
Modification of measles virus and application to pathogenesis studies / Paul Duprex
Bunyavirus reverse genetics and application to interaction with host cells / Richard Elliott
Influenza A virus vaccines / Wendy Barclay
Bluetongue virus reverse genetics / Mark Boyce
Reovirus reverse genetics / Rob Hoeben
Reverse genetics and quasispecies / Marco Vignuzzi
Summary and perspectives / Anne Bridgen.
Notes:
Description based upon print version of record.
Includes bibliographical references and index.
Description based on metadata supplied by the publisher and other sources.
ISBN:
9781118405338
1118405331
9781299190207
1299190200
9781118405352
1118405358
9781118405345
111840534X
OCLC:
792941569

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