Heart transplantation : indications and contradictions, procedures and complications / Catherine T. Fleming, editor.

Format:

Book

Contributor:

Fleming, Catherine T.

Series:

Cardiology Research and Clinical Developments

Cardiology research and clinical developments series

Language:

English

Subjects (All):

Heart--Transplantation.

Heart.

Heart--Surgery.

Physical Description:

1 online resource (313 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Biomedical Books, c2009.

Language Note:

English

Summary:

Cardiac transplantation is a widely accepted therapy for the treatment of end-stage congestive heart failure. Most candidates for transplantation have not been helped by conventional medical therapy & are excluded from other surgical options. This book discusses this topic & includes research from around the world.

Contents:

""Heart Transplantation: Indications and Contradictions, Procedures and Complications""; ""Contents""; ""Preface""; ""Management of Tricuspid Regurgitation After Cardiac Transplantation""; ""Abstract ""; ""Introduction ""; ""Pathophysiology of Tricuspid Valve Regurgitation Following Cardiac Transplantation ""; ""Management of Refractory Tricuspid Regurgitation ""; ""Recent Experience with Repairs and Replacements ""; ""Repair or Replacement? ""; ""Preventing Post-Transplant TR ""; ""Conclusion ""; ""References ""

""Virtual Histology Intravascular Ultrasound in Coronary Allograft Vasculopathy""""References""; ""Gene Therapy for Prevention of Acute and Chronic Cardiac Rejection""; ""Abstract ""; ""1. Introduction ""; "" 2. Antisense Cyclin-Dependent Kinase (cdk) 2 Kinase ODN ""; ""3. Antisense Proliferating-Cell Nuclear Antigen (PCNA) ODN ""; ""4. Antisense Bcl-x ODN""; ""5. E2F Decoy ""; ""6. NF-kB Decoy ""; ""7. Summary ""; ""Acknowledgement""; ""References ""; ""Prevention of Heart Allograft Rejection by Immunotherapy with Ex Vivo-Expanded Foxp3+CD4+CD25+ Natural Regulatory T Cells""; ""Abstract""

""Introduction """"Overview of Foxp3+CD4+CD25+ nTreg Cells ""; ""Foxp3+CD4+CD25+ Treg Cells and Allograft Rejection ""; ""Foxp3+CD4+CD25+ Treg Cells and Allograft Tolerance ""; "" Rationale for Immunotherapy with Foxp3+CD4+CD25+ nTreg Cells ""; ""Strategies and Procedures for Ex Vivo Expansion of CD4+CD25+ nTreg Cells ""; ""Dynamics of Foxp3 Expression during Ex Vivo Expansion ""; ""Suppressive Activity in MLR Assays ""; ""Engraftment, Trafficking and Homing after Adoptive Transfer ""; "" In Vivo Suppression and Allograft Survival ""; ""Determinants of in Vivo Therapeutic Efficacy""

""Issues Regarding CD8+CD25+ nTreg Cells """" Generation and Application of Foxp3+CD4+CD25+ iTreg Cells ""; ""Challenges to Clinical Application ""; ""Conclusion ""; ""References""; ""Addressing the Shortage of Donor Cardiac Allografts - Use of Marginal Grafts""; ""Abstract""; ""Introduction""; ""Strategies to Improve Donor Organ Utilization""; ""Expanding the Use of Marginal Donor Organs""; "" Use of Marginal Cardiac Allografts for Heterotopic Transplantation ""; ""Use of Long Ischemic Time Organs as Marginal Allografts ""; ""Primary Graft Failure as a Consequence of Marginal Graft Use""

""Older Donors and Cardiac Arrest Donors """"Continuous Perfusion of Donor Organs ""; ""Conclusion ""; ""References ""; ""Dendritic Cell Modulation for Therapeutic Immunoregulation in Heart Transplantation""; ""Abstract""; ""Introduction ""; ""Direct and Indirect Allorecognition ""; "" Dendritic Cell Subsets and Dendritic Cell Maturation in Organ Transplantation ""; ""Circulating Dendritic Cells in Human Organ Transplantation ""; ""Therapeutic Strategies Based on Genetically Modified Dendritic Cells ""; ""Therapeutic Modulation of Dendritic Cell Chemoattraction""

""Generation of Regulatory Dendritics Cells ""

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-60876-591-1

OCLC:

872684169