Stem cells research compendium Volume 2 / Prasad S. Koka, editor.

Format:

Book

Contributor:

Koka, Prasad S.

Language:

English

Subjects (All):

Stem cells.

Cytology.

Physical Description:

1 online resource (368 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, c2008.

Language Note:

English

Summary:

As stem cells can be readily grown and transformed into specialised tissues such as muscles or nerves through cell culture, their use in medical therapies has been proposed. This book presents leading research from around the world in this field.

Contents:

Intro

Stem Cells Research Compendium, Volume 2

Contents

Preface

Functional Significance of Active Dye Exclusion by Human Hematopoietic Progenitors after Short-Term Culture

Abstract

Introduction

Material and Methods

Results

Discussion

Acknowledgements

References

The Effects of Ex Vivo Expansion on the Rheology of Umbilical Cord Blood-Derived CD34+ Cells

Materials and Methods

Comparison of the Differentiation Potential of Cell Populations Isolated from Human Lipoaspirate, Trabecular Bone Tissue and Periosteal Tissue

Adult Neural Stem Cells and Their Niches: Developmental and Therapeutic Implications

Neurogenic Niches Exist in the Adult CNS

Neurogenic Niches of the Adult Brain

Developmental Potential of Adult Stem Cells

Therapeutic Implication

Conclusion

Acknowledgments

An Analysis of the Arguments Underpinning UK Embryonic Stem Cell Legislation on the Embryo's Status

Embryo Research before 1990

The Introduction of the Human Fertilisation and Embryology Act 1990

The Debate about Embryonic Stem Cell Research and Cell Nuclear Replacement

Should Early Embryos Be Granted Moral Status?

A Tetracycline-Inducible Lentivector System Based on EF1-α Promoter and Native Tetracycline Repressor Allows In Vivo Gene Induction in Implanted ES Cells

Bone Marrow and Adipose Tissue-Derived Mesenchymal Stem Cells: How Close Are They?

Introduction.

Adipose Tissue: An Alternative to Bone Marrow as a Source of MSC?

Phenotypic Characteristics of Bone Marrow and Adipose Tissue Mesenchymal Stem Cells

Origin of Bone Marrow Mesenchymal Stem Cells: The Relationship with Vascular Mural Cells

Origin of Adipose Tissue Mesenchymal Stem Cells

Pericytes and Vascular Smooth Muscle Cells

MSC as a Hematopoietic Supportive Stroma

From the Bone Marrow to the Periphery: The Ontogeny and Function of Dendritic Cell Populations

DC Diversity in Lymphoid Organs

Ontogeny of DC in the Early Stages of Mouse Development

Molecular Regulation of DC Development

Functional Diversities of DC Subsets

Generation of Steady-State DC Subset Equivalents In Vitro

Concluding Remarks

Advances towards the Development of a Stem Cell Therapy for Hirschsprung's Disease

Factors Regulating ENS Stem Cell Development

Strategy for the Development of a Stem Cell Based Therapy for HSCR: Sources of Stem Cells and Their Properties

Stem Cell Transplantation

The Role of Stem Cells in Repair of Acute Lung Injury

What Is the Acute Respiratory Distress Syndrome and Acute Lung Injury?

Stem Cells in Pulmonary Biology

Where Do Cells That Repair the Lung Originate? (table 2)

Cells Extrinsic to the Lung

Investigations Demonstrating Alveolar Epithelial Repair

Investigations Demonstrating Endothelial Repair

The Role of Injury in Stem Cell Engraftment

How Can Stem Cells Be Used Therapeutically in ALI?

What Are the Persistent Controversies in Stem Cell Research as It Pertains to Lung Repair?

Are Bone Marrow Cells Important in Improving Outcomes for ALI in Humans?

References.

Human Embryonic Stem Cells Undergo Osteogenic Differentiation in Human Bone Marrow Stromal Cell Microenvironments

Hyaluronic Acid Promotes Osteochondrogenic Differentiation from Mesenchymal Stem Cells in a Three-Dimensional Culture System

Cell Cycle Regulation in Maintaining Immortality of Embryonic Stem Cells

Absence of Senescence in ES Cells

Transcriptional Factors and Networks Controlling Self Renewal of hES Cells

Cell Cycle Regulation in Bypassing Senescence

Other Changes Implicating Immortality of Human ES Cells

Potential Target Molecules for Ex Vivo Expansion on Hematopoietic Stem Cells and Their Roles in Normal Hematopoiesis

Characteristic of HSCs

Pilot Trials of Transplantation with Ex Vivo Expanded CB Cells

Acknowledgement

Autotransplantation of Purified Mesenchymal Stem Cells in a Patient with Acute Myocardial Infarction: A Case Study

1. Introduction

2. Materials and Methods

3. Results

4. Discussion

Human Telomerase Catalytic Subunit (hTERT)-Transfected Mesenchymal Stem-Like Cells Derived from Fetal Liver Promote Ex Vivo Expansion of Hematopoietic Stem Cells

Searching for Bone Marrow-Derived Cells in Experimental Models for Renal Injury: Reporter Systems Revisited

BMDC Tracking in the Kidney Using Bone Marrow Transplantation

Ex Vivo Labeling of BMDC.

Summary and Future Perspectives

The Regulatory Function of MicroRNA in Stem Cells

MicroRNA Biogenesis and Its Functions

MicroRNA Expression Profile in Stem Cells

miRNA Expression in Hematopoietic Stem Cells and Progenitors

MicroRNA Regulate Cell Cycles and Stem Cell Division

MicroRNA and Stem Cells Differentiation

MicroRNA Mediated Signal Transduction Pathways in Stem Cells

Niche Theory, Stem-Stromal Imbalance and Aplastic Anaemia

Stem -Stromal Imbalance

Pesticide Induced Acquired Aplastic Anaemia in Human

The Current Hypothesis

Natural Killer Cell Receptor NKG2A/HLA-E Interaction Dependent Differential Thymopoiesis of Hematopoietic Progenitor Cells Influences the Outcome of HIV Infection

I. Introduction

II. Immune Functions in HIV Infection

III. Stem Cell Microenvironment in HIV Infection

IV. Discussion

V. Future Studies

Index.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-60876-923-2

OCLC:

847646525