Chemical synthesis of nucleoside analogues / edited by Pedro Merino.

Format:

Book

Contributor:

Merino, Pedro, 1962-

Language:

English

Subjects (All):

Nucleosides.

Physical Description:

1 online resource (918 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, N.J. : Wiley, c2013.

Language Note:

English

Summary:

Compiles current tested and proven approaches to synthesize novel nucleoside analogues Featuring contributions from leading synthetic chemists from around the world, this book brings together and describes tested and proven approaches for the chemical synthesis of common families of nucleoside analogues. Readers will learn to create new nucleoside analogues with desired therapeutic properties by using a variety of methods to chemically modify natural nucleosides, including:Changes to the heterocyclic baseModification of substituents at the sugar ring</l

Contents:

Deoxynucleoside analogues / Vicente Gotor

Nucleosides modified at the base moiety / Luigi Agrofoglio

Acyclic nucleosides / Antonin Holy

Phosphorylated nucleoside analogues / Giovanni Romeo

Triphosphorylated nucleoside analogues / Chris Meier

Pro-nucleotides / Christian Perigaud

C-nucleoside / Sergio Castillón

Isonucleosides / Vasu Nair

Conformationally constrained nucleosides / Jacques Lebreton

Spironucleosides / Maria Jose Camarasa

L-nucleosides / Daniela Perrone

Carbocyclic nucleosides / Eric Leclerc

Uncommon three-, four, and six-membered nucleosides / Elisabetta Groaz

Thionucleosides / L.S. Jeong

Azanucleosides and related compounds / Tomas Tejero

Oxathiolane and dioxolane nucleosides / Annalisa Guaragna

Isoxazolidinyl nucleosides / Ugo Chiacchio

Nucleoside antibiotics / Apurba Dutta

Building blocks for peptide nucleic acids / Pedro Merino.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record and CIP data provided by publisher; resource not viewed.

ISBN:

1-118-49808-9

1-299-24238-3

1-118-49817-8

OCLC:

825108262