Bioencapsulation in silica-based nanoporous sol-gel glasses / Bouzid Menaa, Farid Menaa and Olga Sharts.

Format:

Book

Author/Creator:

Menaa, Bouzid.

Contributor:

Menaa, Farid.

Sharts, Olga.

Series:

Nanotechnology science and technology series.

Nanotechnology science and technology

Language:

English

Subjects (All):

Biocolloids.

Protein folding.

Silica gel.

Physical Description:

1 online resource (84 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, c2010.

Language Note:

English

Summary:

In this text, the authors report the recent results on the influence of different parameters on the protein conformation based on the design and the characterization of nanoporous silica-based materials containing different functional groups.

Contents:

""BIOENCAPSULATION IN SILICA-BASED NANOPOROUS SOL-GEL GLASSES ""; ""BIOENCAPSULATION IN SILICA-BASED NANOPOROUS SOL-GEL GLASSES ""; ""CONTENTS""; ""PREFACE""; ""ABSTRACT ""; ""1. INTRODUCTION""; ""2. BIOENCAPSULATION VIA SOL-GEL PROCESS IN SILICA-BASED MATERIALS: METHOD, MATERIALS, BIOAPPLICATIONS, AND CHARACTERIZATION TECHNIQUES ""; ""2.1. Protein Bioencapsulation via Sol-Gel Process""; ""2.2. Materials and Bioapplications""; ""2.3. Probing the Silica-Protein Interactions and Protein-Folding""; ""2.3.1. Characterization of the Silica Host Matrix""

""2.3.2. Characterizing the Protein Folding in Nanoporous Sol-Gel Glasses """"3. PARAMETERS INFLUENCING THE PROTEIN CONFORMATION IN NANOPOROUS SILICA-BASED SOL-GEL GLASSES ""; ""3.1. INTRODUCTION TO THERMODYNAMICS� DRIVING FORCES AND INTERACTIONS INFLUENCING THE PROTEIN FOLDING IN SILICA-BASED NANOPOROUS MATERIALS""; ""3.2. The Surface Hydration and Hydrophobicity Influence the Protein Folding in Nanoporous Sol-Gel Glasses ""; ""3.2.1. Hydrophobic Effects on Protein Conformation Induced by Silica Glass Surface Modification with Hydrophobic Organosilanes Precursors ""

""3.2.2. Hydrophobic Effects Induced by the Decrease of siloxane �[O-Si-O]- Network Dimension by Glass Surface Modification with Multiple Hydrophobic Alkyl Groups Attached at the Silicon of Organosilane Precursors""""3.2.3. Solute Effects and Hofmeister Ions Effects""; ""3.3. STERIC EFFECTS INDUCED BY THE CHOICE OF CROWDED SILANE MODIFIERS IN TMOS- DERIVED SOL-GEL GLASSES THE HOST MATRIX ""; ""3.4. INFLUENCE OF THE PORE SIZE, PORE SHAPE AND SURFACE AREA OF THE SILICA-BASED HOST MATRIX ON PROTEIN FOLDING ""; ""3.5. THERMAL STABILITY OF PROTEINS CONFINED IN THE POROUS HOST MATRIX ""

""4. ENHANCING THE PROTEIN FOLDING BY INTRODUCING AND ASSOCIATING HYDROPHOBIC AND STERIC EFFECTS IN MODIFIED SILICA-BASED POROUS GLASSES """"4.1. INCORPORATING FLUORO-BASED ORGANOSILANES IN TO FORM SUPERHYDROPHOBIC CROWDED ORGANICALLY MODIFIED SILICA BASED HOST MATRICES""; ""4.2. INCORPORATING PHOSPHONATE GROUPS IN HYDROPHOBIC SILICA NETWORK ""; ""5. EMERGING TECHNIQUES FOR A BETTER UNDERSTANDING OF PROTEIN INTERACTIONS AND CONFORMATIONS IN NANOPOROUS SOL-GEL GLASSES ""; ""5.1. IN-SITU MAS NMR""; ""5.2. FLUORO-RAMAN SPECTROSCOPY""; ""CONCLUSION ""; ""REFERENCES""; ""INDEX ""

Notes:

Description based upon print version of record.

Includes bibliographical references (p. [51]-66) and index.

Description based on print version record.

ISBN:

1-61761-752-0

OCLC:

923653569