Extremophiles : sustainable resources and biotechnological implications / edited by Om V. Singh.

Format:

Book

Contributor:

Singh, Om V.

Language:

English

Subjects (All):

Extreme environments--Microbiology.

Extreme environments.

Microbial biotechnology.

Physical Description:

1 online resource (472 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, N.J. : Wiley-Blackwell, c2013.

Language Note:

English

Summary:

Explores the utility and potential of extremophiles in sustainability and biotechnology Many extremophilic bio-products are already used as life-saving drugs. Until recently, however, the difficulty of working with these microbes has discouraged efforts to develop extremophilic microbes as potential drug reservoirs of the future. Recent technological advances have opened the door to exploring these organisms anew as sources of products that might prove useful in clinical and environmental biotechnology and drug development. Extremophiles features outstanding articl

Contents:

EXTREMOPHILES; Contents; Contributors; Introduction; 1 MOLECULAR EVOLUTION OF EXTREMOPHILES; 1.1 Introduction; 1.2 Molecular Evolution of Thermophiles; 1.2.1 Habitat; 1.2.2 Cellular Organization; 1.2.3 Genome; 1.2.4 Proteome; 1.3 Molecular Evolution of Psychrophiles; 1.3.1 Habitat; 1.3.2 Cellular Organization; 1.3.3 Genome; 1.3.4 Proteome; 1.4 Molecular Evolution of Halophiles; 1.4.1 Habitat; 1.4.2 Cellular Organization; 1.4.3 Genome; 1.4.4 Proteome; 1.5 Molecular Evolution of Alkaliphiles; 1.5.1 Habitat; 1.5.2 Cellular Organization; 1.5.3 Genome; 1.5.4 Proteome

1.6 Molecular Evolution of Acidophiles1.6.1 Habitat; 1.6.2 Cellular Organization; 1.6.3 Genome; 1.6.4 Proteome; 1.7 Molecular Evolution of Barophiles; 1.7.1 Habitat; 1.7.2 Cellular Organization; 1.7.3 Genome; 1.7.4 Proteome; 1.8 Engineering Extremophiles; 1.8.1 Microbiology; 1.8.2 Molecular Biology; 1.8.3 Bioinformatics; 1.9 Case Studies; 1.9.1 Biofuel Production; 1.9.2 Bioremediation; 1.9.3 Pesticide Biodegradation; 1.9.4 Escherichia coli: A Candidate Extremophile; 1.9.5 Oil-Spill-Cleaning Bacteria; 1.9.6 Potential Applications and Benefits

1.10 Implications of Engineered Extremophiles on Ecology, Environment, and Health1.11 Conclusions and Recommendations; References; 2 ATTAINING EXTREMOPHILES AND EXTREMOLYTES: METHODOLOGIES AND LIMITATIONS; 2.1 Introduction; 2.2 Extremophiles: Types and Diversity; 2.2.1 Thermophiles; 2.2.2 Psychrophiles; 2.2.3 Halophiles; 2.2.4 Alkaliphiles; 2.2.5 Acidophiles; 2.2.6 Barophiles; 2.3 Extremolytes; 2.3.1 Production and Purification of Extremolytes; 2.3.2 Detection, Identification, and Quantification of Extremolytes; 2.3.3 Limitations; 2.4 Conclusions; References

3 STRATEGIES FOR THE ISOLATION AND CULTIVATION OF HALOPHILIC MICROORGANISMS3.1 Introduction; 3.2 Thalassohaline and Athalassohaline Hypersaline Environments; 3.3 Case Studies; 3.3.1 Isolation of Aerobic Chemoheterotrophic Archaea from Solar Salterns; 3.3.2 Magnesium-Requiring and Magnesium-Tolerant Archaea from the Dead Sea; 3.3.3 Isolation of Acidophilic Halophilic Archaea; 3.3.4 Isolation of Unusual Anaerobic Halophiles from Deep-Sea Brines; 3.3.5 Isolation of Polyextremophilic Anaerobic Halophiles; 3.3.6 Isolation of Halophilic Microorganisms Associated with Plants and Animals

3.3.7 Isolation of Halophilic Archaea from Low-Salt Environments3.4 The Upper Salinity Limits of Different Types of Energy Generation; 3.5 Final Comments; References; 4 HALOPHILIC PROPERTIES AND THEIR MANIPULATION AND APPLICATION; 4.1 Introduction; 4.2 Industrial Applications of Halophilic Organisms and Their Proteins; 4.3 Extreme and Moderate Halophiles and Their Proteins; 4.4 Generation of Low-Salt Stable Extreme-Halophilic Proteins; 4.5 Interconversion of Halophilic and Nonhalophilic Proteins; 4.5.1 Dimer-Tetramer Conversion of HaNDK and PaNDK; 4.5.2 Generation of Halophilic PaNDK

4.6 Soluble Expression of Recombinant Proteins

Notes:

Includes index.

Includes bibliographical references and index.

Description based on print version record and CIP data provided by publisher.

ISBN:

9781118394113

1118394119

9781118394144

1118394143

9781283705462

128370546X

9781118394120

1118394127

OCLC:

793099641