Toxicology and epigenetics / editor, Saura C. Sahu.

Format:

Book

Contributor:

Sahu, Saura C.

Language:

English

Subjects (All):

Genetic toxicology.

Environmental toxicology.

Epigenetics.

Physical Description:

1 online resource (1190 p.)

Edition:

1st ed.

Place of Publication:

Chichester, West Sussex, U.K. ; Hoboken, N.J. : John Wiley & Sons, 2012.

Language Note:

English

Summary:

Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel

Contents:

Environment, Epigenetics and Diseases / Robert Y.S. Cheng and Wan-yee Tang

DNA Methylation and Toxicogenomics / Deepti Dileep Deobagkar

Chromatin at the Intersection of Disease and Therapy / Delphine Quénet, Marcin Walkiewicz and Yamini Dalal

Molecular Epigenetic Changes Caused by Environmental Pollutants / Solange S. Lewis, Gregory J. Weber, Jennifer L. Freeman and Maria S. Sepulveda

Epigenetic mediation of environmental exposures to Polycyclic Aromatic Hydrocarbons / Bekim Sadikovic and David I. Rodenhiser

Epigenomic Actions of Environmental Arsenicals / Paul L. Severson & Bernard W. Futscher

Arsenic-induced Changes to the Epigenome / Kathryn A. Bailey and Rebecca C. Fry

Environmental Epigenetics, Asthma and Allergy : Our environment's Molecular Footprints / Stephanie Lovinsky-Desir and Rachel L. Miller

miRNAs in Human Prostate Cancer / Ernest K. Amankwah and Jong Y. Park

Environment, Epigenetics and Cardiovascular Health / Sanjukta Ghosh and Andrea Baccarelli

Toxicology, Epigenetics and Autoimmunity / Craig A. Cooney and Kathleen M. Gilbert

Toxicoepigenomics in Lupus / Donna Ray and Bruce C. Richardson

Ocular Epigenomics : Potential Sites of Environmental Impact in Development and Disease / Kenneth P. Mitton

Nuclear RNA Silencing and Related Phenomena in Animals / Radek Malik and Petr Svoboda

Epigenetic Biomarkers in Cancer Detection and Diagnosis / Ashley G. Rivenbark and William B. Coleman

Epigenetic Histone Changes in the Toxicologic mode of action of Arsenic / John F. Reichard and Alvaro Puga

Irreversible Effect of Diethylstilbestrol on Reproductive Organs and Current Approach for Epigenetic Effects of Endocrine Disrupting Chemicals / Shinichi Miyagawa, Ryohei Yatsu, Tamotsu Sudo, Katsuhide Igarashi, Jun Kanno, and Taisen Iguchi

Epigenomics : Impact for Drug Safety Sciences / Harri Lempiäinen, Raphaelle Luisier, Arne Muller, Philippe Marc, David Heard, Federico Bolognani, Pierre Moulin, Philippe Couttet, Olivier Grenet, Jennifer Marlowe, Jonathan Moggs, and Rémi Terranova

Archival Toxicoepigenetics : Molecular Analysis of Modified DNA from Preserved Tissues in Toxicology Studies / B. Alex Merrick

Nanoparticles and Toxicoepigenomics / Manasi P. Jain, Angela O. Choi, and Dusica Maysinger

Methods of Global Epigenomic Profiling / Michael W.Y. Chan, Zhengang Peng, Jennifer R. Chao, Yingwei Li, Matthew T. Zuzolo, and Huey-Jen L. Lin

Transcriptomics : Applications in Epigenetic Toxicology / Pius Joseph

Carcinogenic metals alter histone tail modifications / Yana Chervona and Max Costa

Prediction of epigenetic and stochastic gene expression profiles of late effects after radiation exposure / Yoko Hirabayashi and Tohru Inoue

Modulation of developmentally regulated gene expression programs through targeting of polycomb and trithorax group proteins / Marjorie Brand and F. Jeffrey Dilworth

Chromatin Insulators and Epigenetic Inheritance in Health and Disease / Jingping Yang and Victor G. Corces

Bioinformatics for High-Throughput Toxico-epigenomics Studies / Maureen A. Sartor, Dana C. Dolinoy, Laura S. Rozek, and Gilbert S. Omenn

Computational Methods in Toxicoepigenomics / Joo Chuan Tong

Databases and Tools for Computational Epigenomics / V. Umashankar and S. Gurunathan

Interface of Epigenetics and Carcinogenic Risk Assessment / Paul Nioi

Epigenetic Modifications in Chemical Carcinogenesis / Igor P. Pogribny, Igor Koturbash, and Frederick A. Beland

Application of Cancer Toxicoepigenomics in Identifying High-Risk Populations / Mukesh Verma and Krishna K Banaudha.

Notes:

Description based upon print version of record.

Description based on print version record and CIP data provided by publisher.

Includes bibliographical references and index.

ISBN:

9786613905192

9781118349069

1118349067

9781283592741

1283592746

9781118349045

1118349040

9781118349038

1118349032

OCLC:

793497223