Translational animal models in drug discovery and development / editor Xinkang Wang.

Format:

Book

Author/Creator:

Wang, Xinkang, Author.

Contributor:

Wang, Xinkang.

Language:

English

Subjects (All):

Animal models in research.

Medicine--Research.

Medicine.

Physical Description:

1 online resource (287 p.)

Edition:

1st ed.

Place of Publication:

[S.l.] : Bentham Science Publishers, 2012.

Language Note:

English

Summary:

Animal models of diseases play a pivotal role in drug discovery and development, not only for proof of the concept studies of efficacy, PK/PD relationship but also for drug safety assessment. Since considerable differences in variables exist between animal models and human models (such as genetics, physiology, anatomy, gene expression, heterogeneity of disease conditions, etc.), not all the preclinical models are able to represent the pathophysiological conditions in human diseases. Therefore, partly due to the lack of congruency between animal and human disease models, several proposed therap

Contents:

Cover; Title; EUL; Contents; Foreword; Preface; List of Contributors; Chapter 01; Chapter 02; Chapter 03; Chapter 04; Chapter 05; Chapter 06; Chapter 07; Chapter 08; Chapter 09; Chapter 10; Index

Notes:

Description based upon print version of record.

Includes bibligraphical references and index.

ISBN:

9781608054695

1608054691

OCLC:

818819309