Targets and emerging therapies for schizophrenia / edited by Jeffrey S. Albert, Michael W. Wood.

Format:

Book

Contributor:

Albert, Jeffrey S.

Wood, Michael W. (Michael William), 1961-

Language:

English

Subjects (All):

Schizophrenia--Treatment.

Schizophrenia.

Physical Description:

1 online resource (492 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, N.J. : Wiley, 2012.

Language Note:

English

Summary:

New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover, many schizophrenia patients fail to respond to current antipsychotics. Integrating chemistry, biology, and pharmacology, this book explores emerging directions in pharmaceutical research for drug targeting and discovery in order to find more effective treatments for schizophrenia, one of the most serious and widesp

Contents:

Dopaminergic hypothesis of schizophrenia : a historical perspective / Aurelija Jucaite and Svante Nyberg

Dopamine D2/D3 partial agonists as antipsychotics / Philip G. Strange

D1/D5 dopamine agonists as pharmacotherapy for schizophrenia / Kevin N. Boyd and Richard B. Mailman

PDE inhibitors as a novel therapeutic approach for schizophrenia / Judith A. Siuciak and William J. Pitts

Glutamatergic synaptic dysregulation in schizophrenia / Joseph T. Coyle, Alo Basu, and Michael Benneyworth

Metabotropic glutamate 2/3 receptor agonists and positive allosteric modulators of metabotropic glutamate receptor 2 as novel agents for the treatment of schizophrenia / Gerard J. Marek ... [et al.]

AMPA receptor positive modulators / John A. Morrow, John K.F. Maclean, and Craig Jamieson

Progress in the exploration and development of GlyT1 inhibitors for schizophrenia / Jeffrey S. Albert and Michael W. Wood

Combined dopamine D2 and 5-hydroxytryptamine (5-HT)1a receptor strategies for the treatment of schizophrenia, a pharmacological and chemical perspective / Andrew C. Mccreary, Roelof W. Feenstra, and Caitlin A. Jones

5-HT2C and 5-HT6 receptor targeted emerging approaches in schizophrenia / Sharon Rosenzweig-Lipson ... [et al.]

The cholinergic hypothesis : an introduction to the hypothesis and a short history / Joseph I. Friedman, Isabella Kanellopoulou, and Vladan Novakovic

À7 nicotinic acetylcholine receptors in the treatment of schizophrenia / Mihály Hajós, and Bruce N. Rogers

Muscarinic acetylcholine receptors as novel targets for the development of therapeutics for schizophrenia / Christian C. Felder ... [et al.]

Will modulation of neuropeptide receptors produce the next generation of antipsychotic drugs? : a focus on the neurokinin and neurotensin systems / Lee A. Dawson, Paul W. Smith, and Jeannette M. Watson

GABA and schizophrenia / John H. Kehne and George D. Maynard.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9786613676290

9781280699313

1280699310

9781118309407

1118309405

9781118309421

1118309421

9781118309384

1118309383

OCLC:

769289644