Enzymes in organic synthesis / [editors: Ruth Porter (organizer) and Sarah Clark.

Format:

Book

Conference/Event

Contributor:

Porter, Ruth.

Clark, Sarah.

Ciba Foundation.

Conference Name:

Symposium on Organic Synthesis Using Enzymes (1984 : Ciba Foundation)

Series:

Ciba Foundation symposium ; 111.

Ciba Foundation symposium ; 111

Language:

English

Subjects (All):

Organic compounds--Synthesis--Congresses.

Organic compounds.

Enzymes--Congresses.

Enzymes.

Physical Description:

1 online resource (258 pages) : illustrations

Edition:

1st ed.

Place of Publication:

London : Pitman ; Newark, N.J. : Distributed in North America by CIBA Pharmaceutical Co. (Medical Education Division), 1985.

Language Note:

English

Summary:

The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.

Contents:

Enzymes in organic synthesis; Contents; Chairman's introduction; An illustrative example of a synthetically useful enzyme: horse liver alcohol dehydrogenase; Discussion; Enzymic synthesis of labelled chiral substances; Discussion; Enzyme-controlled reactions giving alkanols of use in the synthesis of biologically active molecules; Discussion; Large-scale purification of enzymes; Discussion; Immobilized enzymes in organic synthesis; Discussion; General discussion I Synthesis of 5,6-dihydroxycyclohexa-l,3-die; Applications of cell-free enzymes in organic synthesis; Discussion

Chiral products from non-pyridine nucleotide-dependent reductases and methods for NAD(P)H regeneration Discussion; Stereochemistry and synthetic applications of products of fermentation of a,p-unsaturated aromatic aldehydes by baker's yeast; Discussion; Extending the applicability of esterases of low enantioselectivity in asymmetric synthesis; Discussion; Microbial transformations of some monoterpenoids and sesquiterpenoids; Discussion; General discussion I1 Synthesis of tetrahydrofolate derivatives; Synthesis of optically active propylene oxides

Creation of novel chiral synthons with enzymes: application to enantioselective synthesis of antibiotics Discussion; Kinetics of trypsin catalysis in the industrial conversion of porcine insulin to human insulin; Discussion; Redesigning enzymes by site-directed mutagenesis; Discussion; The design of new enzyme active sites for the catalysis of specific chemical reactions; Discussion; Final general discussion NAD+ degradation by resting cells; Economic aspects; Applications of enzyme methodology; Index of contributors; Subject index

Notes:

"Symposium on Organic synthesis using enzymes, held at the Ciba Foundation, London, 15-17 May 1984"--Contents page.

Includes bibliographical references and indexes.

ISBN:

9786613694546

9781280784156

1280784156

9780470720929

0470720921

9780470718629

0470718625

OCLC:

797918527