Lead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds / Florencio Zaragoza Dörwald.

Format:

Book

Author/Creator:

Dörwald, Florencio Zaragoza.

Language:

English

Subjects (All):

Pharmacokinetics.

Drug development.

Physical Description:

1 online resource (623 p.)

Edition:

1st ed.

Place of Publication:

Weinheim, Germany : Wiley-VCH, 2012.

Language Note:

English

Summary:

Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy

Contents:

pt. 1. Introduction

pt. 2. The pharmacokinetic properties of compound classes.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

3-527-64564-0

1-283-89324-X

3-527-64566-7

OCLC:

805654697