Pharmacokinetics in everyday clinical practice / Federico Pea.

Format:

Book

Author/Creator:

Pea, Federico.

Language:

English

Subjects (All):

Pharmacokinetics.

Pharmacology.

Physical Description:

1 online resource (112 p.)

Edition:

1st ed.

Place of Publication:

Torino : SEEd, 2012.

Language Note:

English

Summary:

This book provides a practical introduction to the main concepts of pharmacokinetics and how they can be applied in clinical settings, without using complicated mathematical equations. Essential information on approaches to drug-dosing and monitoring in special populations, including patients with renal and hepatic diseases and elderly patients, are given. Charts, illustrations and examples of calculations are added to clarify concepts and terminology of pharmacokinetics. It's a guide for students and clinicians who want clear, useful guidance to the basic principles of pharmacokinetics and th

Contents:

Colophon; Table of contents; Introduction; 1Pharmacokinetics and Terminology; 1.1Oral Bioavailability (Fos); 1.2Apparent Volume of Distribution (Vd); 1.3Plasma Clearance (CL); 1.4Area Under the Plasma Concentration-time Curve (AUC); 1.5Plasma Elimination Half-life (t1/2); 1.6Steady State Plasma Concentration (Css); 1.7Loading Dose (LD); 1.8Maintenance Dose (MD); 2Pharmacokinetics and Polytherapy; 2.1Cytochrome P450 (CYP); 2.2P170 Glycoprotein (Pgp); 3Pharmacokinetics and Dosing Regimen; 4Pharmacokinetics and Patient Pathophysiology; 4.1Age; 4.2Renal Failure; 4.3Hepatic Failure

4.4The Critically Ill Patient5Pharmacokinetics and Pharmaceutical Technology; 5.1Liposomal Formulations; 5.2Controlled Release or Depot Formulations; 5.3Prodrugs; 6Pharmacokinetics and Pharmacogenetics; 6.1Polymorphism of Phase I Enzymes; 6.2Polymorphism of Phase II Enzymes; 7Pharmacokinetics and Pharmacodynamics; 7.1Pharmacokinetic-pharmacodynamic (PK/PD) Relationships in Antibiotic Therapy; 7.2Pharmacokinetic-pharmacodynamic (PK/PD) Relationships in Antifungal Therapy; 8Conclusions; References; Glossary; Author

Notes:

Description based upon print version of record.

Includes bibliographical references.

ISBN:

88-97419-18-6

OCLC:

781615014