Pharmacogenetics and individualized therapy / edited by Anke-Hilse Maitland-van der Zee, Ann K. Daly.

Format:

Book

Contributor:

Maitland-van der Zee, Anke-Hilse.

Daly, Ann K.

Language:

English

Subjects (All):

Pharmacogenetics.

Physical Description:

1 online resource (506 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, N.J. : John Wiley & Sons, c2011.

Language Note:

English

Summary:

This resource provides thorough coverage of pharmacogenetics and its impact on pharmaceuticals, therapeutics, and clinical practice. It opens with the basics of pharmacogenetics, including drug disposition and pharmacodynamics. The following section moves into specific disease areas, including cardiovascular, psychiatry, cancer, asthma/COPD, adverse drug reactions, transplantation, inflammatory bowel disease, and pain medication. Clinical practice and ethical issues make up the third section, with the fourth devoted to technologies like genotyping, genomics, and proteomics. In the fifth part,

Contents:

Pharmacogenetics : a historical perspective / A.K. Daly

Pharmacogenetics in drug metabolism : role of phase I enzymes / V. Dolzan

Pharmacogenetics of phase II drug metabolizing enzymes / I. Cascorbi

Pharmacogenetics of drug transporters / Henriette E. Meyer zu Schwabedissen, Markus Grube, Heyo K. Kroemer

Pharmacogenetics of drug targets / M.Arranz and A. Daly

Cardiovascular pharmacogenetics / Bas J.M. Peters ... [et al.]

Pharmacogenetics in psychiatry / Evangelia M. Tsapakis ... [et al.]

Pharmacogenetics in cancer / S. Marsh

Pharmacogenetics of asthma and COPD / E. Koster ... [et al.]

Pharmacogenetics of adverse drug reactions / Ann K Daly, Martin Armstrong, and Munir Pirmohamed

Pharmacogenomics of inflammatory bowel diseaes / Alexander Teml ... [et al.]

Pharmacogenetics of pain medication / J. Loetsch

Ethical and social issues in pharmacogenomics testing / S. Vijverberg, T. Pieters, and M. Cornel

High-throughput genotyping technologies for pharmacogenetics / Beatriz Sobrino and Dr. Angel Carracedo

Developments in analyses in pharmacogenetic datasets / A. Motsinger

Applications of pharmacogenetics in pharmaceutical research and development / Daniel K. Burns and Scott S. Sundseth

Role of pharmacogenetics in registration process / Myong-Jin Kim ... [et al.]

Pharmacogenetics : possibilities and pitfalls / A.H. Maitland-van der Zee and A.K. Daly.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9786613620330

9781280590504

1280590505

9781118116487

1118116488

9781118116494

1118116496

9781118116463

1118116461

OCLC:

784883612