Immunotherapy in transplantation : principles and practice / edited by Bruce Kaplan, Gilbert J. Burckart, Fadi G. Lakkis.

Format:

Book

Contributor:

Kaplan, Bruce, 1958-

Burckart, Gilbert J.

Lakkis, Fadi G.

Language:

English

Subjects (All):

Immunotherapy.

Transplantation immunology.

Physical Description:

1 online resource (485 p.)

Edition:

1st ed.

Place of Publication:

West Sussex : John Wiley, 2012.

Language Note:

English

Summary:

This comprehensive reference source will benefit all transplant specialists working with pharmacologic and biologic agents that modulate the immune system. Compiled by a team of world-renowned editors and contributors covering the fields of transplantation, nephrology, pharmacology, and immunology, the book covers all anti-rejection drugs according to a set template and includes the efficacy of each for specific diseases.

Contents:

Immunotherapy in Transplantation: Principles and Practice; Contents; List of Contributors; Preface; Part 1 Transplantation Immunobiology; 1 The Immune Response to a Transplanted Organ: An Overview; 2 Antigen Presentation in Transplantation; 3 The T Cell Response to Transplantation Antigens; 4 The B Cell Response to Transplantation Antigens; 5 The Innate Response to a Transplanted Organ; 6 Regulation of the Alloimmune Response; Part 2 Transplantation Clinical Pharmacology; 7 Pharmacokinetics; 8 Therapeutic Drug Monitoring for Immunosuppressive Agents

9 Pharmacometrics: Concepts and Applications to Drug Development10 Pharmacogenomics and Organ Transplantation; 11 Study Design/Process of Development: Clinical Studies; Part 3 Agents; 12 Corticosteroids; 13 Azathioprine; 14 Pharmacokinetic and Pharmacodynamic Properties of Mycophenolate; 15 Cyclosporine: Molecular Action to Clinical Therapeutics; 16 Tacrolimus; 17 Inhibitors of Mammalian Target of Rapamycin; 18 Inhibitors Targeting JAK3; 19 Cyclophosphamide; 20 Application of Antisense Technology in Medicine; 21 The Role of Ganciclovir in Transplantation

22 Transplantation Immunotherapy with Antithymocyte Globulin (ATG)23 The Role of Alemtuzumab in Solid Organ Transplantation; 24 Rituximab, an Anti-CD20 Monoclonal Antibody; 25 The Anti-Interleukin 2 Receptor Antibodies; 26 Infliximab/Anti-TNF; 27 CTLA4-Ig; 28 Combination and Adjuvant Therapies to Facilitate the Efficacy of Costimulatory Blockade; 29 Intravenous Immunoglobulin (IVIG) a Modulator of Immunity and Inflammation with Applications in Solid Organ Transplantation; Index; Color Plates

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-280-58641-9

9786613616241

1-4443-5562-7

1-4443-5543-0

OCLC:

777375710