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The AH receptor in biology and toxicology / edited by Raimo Pohjanvirta.
- Format:
- Book
- Language:
- English
- Subjects (All):
- Polycyclic aromatic hydrocarbons--Toxicology.
- Polycyclic aromatic hydrocarbons.
- Polycyclic aromatic hydrocarbons--Metabolism.
- Dioxins--Toxicology.
- Dioxins.
- Dioxins--Metabolism.
- Nuclear receptors (Biochemistry).
- Transcription factors.
- Physical Description:
- 1 online resource (558 p.)
- Edition:
- 1st ed.
- Place of Publication:
- Hoboken, N.J. : Wiley, c2012.
- Language Note:
- English
- Summary:
- This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases.
- Contents:
- pt. 1. Historical background
- pt. 2. AHR as a ligand-activated transcription factor
- pt. 3. AHR as a mediator of xenobiotic toxicities : dioxins as a key example
- pt. 4. AHR as a physiological regulator.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- Description based on publisher supplied metadata and other sources.
- ISBN:
- 9786613400956
- 9781283400954
- 1283400952
- 9781118140574
- 1118140575
- 9781118140567
- 1118140567
- 9781118140543
- 1118140540
- OCLC:
- 779166476
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