Von Willebrand disease : basic and clinical aspects / edited by Augusto B. Federici ... [et al.].

Format:

Book

Contributor:

Federici, Augusto B.

Language:

English

Subjects (All):

Von Willebrand disease.

Blood coagulation disorders.

Physical Description:

1 online resource (268 p.)

Edition:

1st ed.

Place of Publication:

Chichester, West Sussex ; Hoboken, NJ : Wiley-Blackwell, 2011.

Language Note:

English

Summary:

Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology,

Contents:

Von Willebrand Disease: Basic and Clinical Aspects; Contents; Contributors; Foreword; Preface; 1: Historical perspective on von Willebrand disease; 2: Biosynthesis and organization of von Willebrand factor; 3: von Willebrand factor structure and function; 4: Modulation of von Willebrand factor by ADAMTS 13; 5: Animal models in von Willebrand disease; 6: Classification of von Willebrand disease; 7: The epidemiology of von Willebrand disease; 8: Clinical aspects of von Willebrand disease: bleeding history; 9: Laboratory diagnosis of von Willebrand disease: the phenotype

10: Molecular diagnosis of von Willebrand disease: the genotype11: Clinical, laboratory, and molecular markers of type 1 von Willebrand disease; 12: Clinical, laboratory, and molecular markers of type 2 von Willebrand disease; 13: Clinical, laboratory, and molecular markers of type 3 von Willebrand disease; 14: Pediatric aspects of von Willebrand disease; 15: Women with von Willebrand disease; 16: On the use of desmopressin in von Willebrand disease; 17: The use of plasma - derived concentrates; 18: Prophylaxis in von Willebrand disease

19: Pathophysiology, epidemiology, diagnosis, and treatment of acquired von Willebrand syndrome20: Gene therapy for von Willebrand disease; Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-283-40714-0

9786613407146

1-4443-2993-6

1-4443-2992-8

OCLC:

711779452