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Reproductive endocrinology for the MRCOG and beyond / edited by Adam Balen.

Ebook Central Academic Complete Available online

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Format:
Book
Contributor:
Balen, Adam H., editor.
Series:
MRCOG and beyond series.
MRCOG and beyond series
Language:
English
Subjects (All):
Human reproduction--Endocrine aspects.
Human reproduction.
Physical Description:
1 online resource (xii, 214 pages) : digital, PDF file(s).
Edition:
Second edition.
Other Title:
Reproductive Endocrinology for the MRCOG & Beyond
Place of Publication:
London : RCOG Press, 2007.
Summary:
Understanding endocrinology is central to understanding the key processes that affect normal reproductive function, while an understanding of normal endocrinology and the pathophysiology of endocrine disorders is important when dealing with reproductive disorders. This book provides a comprehensive background for all gynaecologists, covering: sexual differentiation and intersex disorders; adrenal disorders; normal puberty and adolescence; abnormal puberty; the menstrual cycle; disorders of menstruation; amenorrhoea; polycystic ovary syndrome; anovulatory fertility and ovulation induction; lactation and lactational amenorrhoea; hyperprolactinaemia; thyroid disease; diabetes; lipid metabolism and lipoprotein transport; premature ovarian failure; and calcium metabolism and its disorders. The book is primarily designed to provide a comprehensive summary for candidates preparing for the Part 2 MRCOG examination, and as such covers the RCOG curriculum for reproductive endocrinology. It is also a valuable guide for all healthcare professionals working in the field, including trainees, consultants and any health professional coming into contact with women.
Contents:
Cover
Published titles in the MRCOG and Beyond series
Contents
Acknowledgments
Preface to the first edition
Preface to the second edition
Abbreviations
1. Sexual differentiation: intersex disorders
Development of the internal and external genitalia
Origin of the ovaries and oocytes
Origin of the uterus and fallopian tubes
Development of external genitalia
NEWBORN APPEARANCE
Disorders of development of internal andexternal genitalia
MULLERIAN DUCT ABNORMALITIES
CONGENITAL ABSENCE OF THE VAGINA
FUSION ABNORMALITIES OF THE VAGINA
MULLERIAN/UTERINE ANOMALIES
Androgen insensitivity syndrome
5-ALPHA REDUCTASE DEFICIENCY
Congenital adrenal hyperplasia
Cloacal anomalies
Management of intersex conditions
Reference
2. Adrenal disorders
The adrenal medulla
EFFECTS OF ADRENALINE AND NORADRENALINE
PHAEOCHROMOCYTOMA
The adrenal cortex
HYPERFUNCTION OF THE ADRENAL CORTEX
3. Normal puberty and adolescence
Pubertal development
ONSET OF PUBERTAL DEVELOPMENT
References
4. Abnormal puberty
Precocious puberty
TRUE PRECOCIOUS PUBERTY
PREMATURE THELARCHE
THELARCHE VARIANT
PREMATURE ADRENARCHE
CONGENITAL ADRENAL HYPERPLASIA
PERIPHERAL TUMOURS
MANAGEMENT OF PRECOCIOUS PUBERTY
CONSTITUTIONAL DELAY OF GROWTH AND PUBERTY
TURNER SYNDROME
POLYGLANDULAR AUTOIMMUNE SYNDROMES
CONGENITAL HYPOGONADOTROPHIC HYPOGONADISM
MANAGEMENT OF DELAYED PUBERTY
Delayed puberty
5. The menstrual cycle
Ovulation during the perimenopausal transition
6. Disorders of menstruation
Normal menstruation
VARIATION IN MENSTRUAL BLOOD LOSS.
VARIATION IN CYCLE LENGTH AND DURATION OF MENSTRUATION
The abnormal menstrual cycle
MENORRHAGIA
ASSESSMENT OF MENSTRUAL BLOOD LOSS
CAUSES OF MENORRHAGIA
DIAGNOSIS OF MENORRHAGIA
Methods of endometrial assessment
ENDOMETRIAL BIOPSY
HYSTEROSCOPY
TRANSVAGINAL ULTRASOUND
Initial management of menorrhagia in primary care
Medical treatment of menorrhagia
NON-HORMONAL TREATMENTS
HORMONAL TREATMENTS
TREATMENT FAILURES
Surgical treatment of menorrhagia
HYSTERECTOMY
OVARIES AND HYSTERECTOMY
ENDOMETRIAL ABLATIVE TECHNIQUES
COMPARISON OF ENDOMETRIAL ABLATIVE TECHNIQUES WITH HYSTERECTOMY
Counselling in menorrhagia
The ideal management of menorrhagia
Fibroids
MANAGEMENT
Dysmenorrhoea
PRIMARY DYSMENORRHOEA
SECONDARY DYSMENORRHOEA
TREATMENT
ASSESSMENT
7. Amenorrhoea
Primary amenorrhoea
Secondary amenorrhoea
Examination and investigation of amenorrhoea
Causes of amenorrhoea
GENITAL TRACT ABNORMALITIES
SYSTEMIC DISORDERS CAUSING SECONDARY AMENORRHOEA
WEIGHT-RELATED AMENORRHOEA
LEPTIN
PSYCHOLOGICAL STRESS
EXERCISE-RELATED AMENORRHOEA
HYPOTHALAMIC CAUSES OF SECONDARY AMENORRHOEA
PITUITARY CAUSES OF SECONDARY AMENORRHOEA
IATROGENIC CAUSES OF AMENORRHOEA
8. Polycystic ovary syndrome
Pathogenesis
GENETICS OF POLYCYSTIC OVARY SYNDROME
HETEROGENEITY OF POLYCYSTIC OVARY SYNDROME
Management of polycystic ovary syndrome
OBESITY
MENSTRUAL IRREGULARITY
INFERTILITY
HYPERANDROGENISM AND HIRSUTISM
9. Health consequences of polycystic ovary syndrome
Insulin resistance
Insulin resistance in polycystic ovary syndrome
Other risk factors for ischaemic heart disease in women with polycystic ovary syndrome
CENTRAL OBESITY
IMPAIRED GLUCOSE TOLERANCE AND DIABETES
HYPERTENSION
DYSLIPIDAEMIA.
HYPERHOMOCYSTEINAEMIA
Polycystic ovary syndrome in younger women
Long-term follow-up in polycystic ovary syndrome
Therapeutic options
Polycystic ovary syndrome and cancer
ENDOMETRIAL CANCER
BREAST CANCER
OVARIAN CANCER
10. Anovulatory infertility andovulation induction
Pituitary and hypothalamic causes of anovulation
HYPOGONADOTROPHIC HYPOGONADISM
Polycystic ovary syndrome (see also Chapter 8)
LIFESTYLE AND WEIGHT LOSS IN POLYCYSTIC OVARY SYNDROME
CLOMIFENE CITRATE THERAPY
AROMATASE INHIBITORS
GONADOTROPHIN THERAPY
SURGICAL OVULATION INDUCTION
THE ROLE OF METFORMIN AND OTHER INSULIN SENSITISERS
IVF IN WOMEN WITH POLYCYSTIC OVARIES
IN VITRO MATURATION OF OOCYTES
Risks of ovulation induction
Ovarian hyperstimulation syndrome
MANAGEMENT OF OVARIAN HYPERSTIMULATION SYNDROME
Summary
11. Lactation and lactational amenorrhoea
Initiation of lactation
Maintenance of lactation and milk letdown
Endocrine effects of lactation
AMENORRHOEA
HYPOESTROGENAEMIA
SOCIAL EFFECTS
Metabolic effects of lactation
DIET
WEIGHT CHANGE
CONTROL OF LACTATION
Lactation and contraception
NATURAL CONTRACEPTION
ARTIFICIAL CONTRACEPTION
12. Hyperprolactinaemia
MEDICAL MANAGEMENT
SURGICAL MANAGEMENT
EFFECT ON PREGNANCY
13. Thyroid disease
Scientific background
Thyroid function
CLINICAL EXAMINATION OF THE THYROID GLAND
Classification and diagnosis (Table 13.2)
SIMPLE NON-TOXIC GOITRE
HYPOTHYROIDISM
HYPERTHYROIDISM
14. Diabetes
Definition
Treatment and control
Relevance to fertility
Relevance to pregnancy
Management of diabetes in pregnancy
Managing the complications of diabetes inpregnancy.
Managing the complications of pregnancy in women with diabetes
Type 2 diabetes, hyperinsulinaemia and insulin resistance
15. Lipid metabolism and lipoprotein transport
Transport of dietary fat
HEPATIC LIPID METABOLISM
ENDOGENOUS LIPID TRANSPORT
HIGH-DENSITY LIPOPROTEINS AND REVERSE CHOLESTEROL TRANSPORT
The effect of menopause on plasma lipoproteins
16. Premature ovarian failure
The control of ovarian ageing
Definition and diagnosis
Causation
GENETIC CAUSES
FAMILIAL FACTORS
AUTOIMMUNE CAUSES
Management
OOCYTE DONATION
CRYOPRESERVATION OF OVARIAN TISSUE
17. Calcium metabolism and its disorders
Calcium and bone homeostasis
Parathyroid hormone and calcium
Renal disease and calcium
Osteoporosis and calcium
Appendix: Endocrine normal ranges
Further reading
Index.
Notes:
Title from publisher's bibliographic system (viewed on 05 Oct 2015).
Includes bibliographical references and index.
ISBN:
1-107-71091-X
1-107-71433-8
9786611894320
1-281-89432-X
1-904752-72-1
1-139-69692-0
OCLC:
923353383

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