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Development of vaccines : from discovery to clinical testing / edited by Manmohan Singh, Indresh K. Srivastava.
- Format:
- Book
- Language:
- English
- Subjects (All):
- Vaccines.
- Drug development.
- Drug stability.
- Physical Description:
- 1 online resource (478 p.)
- Edition:
- 1st ed.
- Place of Publication:
- Hoboken, N.J. : John Wiley & Sons, c2011.
- Language Note:
- English
- Summary:
- Development of Vaccines: From Discovery to Clinical Testing outlines the critical steps, and analytical tools and techniques, needed to take a vaccine from discovery through a successful clinical trial. Contributions from leading experts in the critical areas of vaccine expression, purification, formulation, pre-clinical testing and regulatory submissions make this book an authoritative collection of issues, challenges and solutions for progressing a biologic drug formulation from its early stage of discovery into its final clinical testing. A section with details and real-life experien
- Contents:
- Microbial vaccines design : the reverse vaccinology approach / Roberto Rosini, Michele A. Barocchi, Rino Rappuoli
- Design and development of recombinant vaccines with viral properties / Gerd Lipowsky, Martin F. Bachmann
- Tools for vaccine design : prediction and validation of highly immunogenic and conserved class II epitopes, and development of epitope-driven vaccines / Anne S. De Groot ... [et al.]
- Virus like-particle vaccines advantages and challenges / Ted M. Ross ... [et al.]
- Design platforms of nanocapsules for human therapeutics or vaccines / Masaaki Kawano ... [et al.]
- Designing immunogens for vaccine development in reference to HIV / Aemro Kassa ... [et al.]
- Expression and purification of recombinant proteins for vaccine applications / Carlo Zambonelli, Deeann Martinez-Guzmann, and Indresh K. Srivastava
- DNA vaccines for infectious diesase / Samuel Stepenson, Manmohan Singh, Indresh K. Srivastava
- Developing stable cell lines for the production of vaccine antigens / Xiaotian Zhong ... [et al.]
- Spectroscopy of vaccines / C. Russell Middaugh, Sangeeta B. Joshi
- Biophysical characterization of protein antigens within vaccine formulations / Padima Malyala, Derek O'Hagan, Manmohan Singh
- Structural characteristics predict the stability of HIV / Zohar Biron ... [et al.]
- Selection of optimal adjuvants and product factors that affect vaccine immunogenicity / Wei Wang, Manmohan Singh
- Lyophilization and stabilization of vaccines / James Chesko ... [et al.]
- Effect of buffers and stabilizers on vaccine stability and efficacy / Shireesh P. Apte, Sydney Ugwu
- Selection of final product containers / Luis Baez, Adrian Distler
- From the lab to the clinic : filing a phase I IND for an investigational vaccine / Kenneth G. Surowitz.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- ISBN:
- 9786613175656
- 9781283175654
- 1283175657
- 9781118023631
- 1118023633
- 9781118023648
- 1118023641
- 9781118023624
- 1118023625
- OCLC:
- 739118473
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