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Carbohydrate recognition : biological problems, methods, and applications / edited by Binghe Wang, Geert-Jan Boons.
- Format:
- Book
- Series:
- Wiley series in drug discovery and development.
- Wiley series in drug discovery and development
- Language:
- English
- Subjects (All):
- Carbohydrates--Therapeutic use.
- Carbohydrates.
- Physical Description:
- 1 online resource (450 p.)
- Edition:
- 1st ed.
- Place of Publication:
- Hoboken, N.J. : Wiley, c2011.
- Language Note:
- English
- Summary:
- "This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition"--Provided by publisher.
- Contents:
- CARBOHYDRATE RECOGNITION; PREFACE; CONTRIBUTORS; 1 MAMMALIAN GLYCAN BIOSYNTHESIS: BUILDING A TEMPLATE FOR BIOLOGICAL RECOGNITION; 2 THE ROLES OF CARBOHYDRATE BINDING IN CELL ADHESION AND INFLAMMATION; 3 THE ROLE OF CARBOHYDRATES IN VIRAL INFECTIONS; 4 THE ROLE OF CARBOHYDRATES IN BACTERIAL INFECTIONS; 5 THE ROLES OF CARBOHYDRATE BINDING IN FERTILIZATION; 6 CARBOHYDRATE BIOMARKERS; 7 GALECTINS AND THEIR ROLE IN VARIOUS BIOLOGICAL PROCESSES; 8 GLYCOIMMUNOLOGY; 9 TOOLS FOR GLYCOMICS: GLYCAN AND LECTIN MICROARRAYS; 10 COMBINATORIAL BIOSYNTHESIS OF COMPLEX CARBOHYDRATES
- 11 MASS SPECTROMETRY IN CARBOHYDRATE SEQUENCING AND BINDING ANALYSIS12 SYNTHETIC LECTIN MIMICS ARTIFICIAL CARBOHYDRATE RECEPTORS; 13 LECTIN BINDING AND ITS STRUCTURAL BASIS; 14 MULTIVALENCY IN CARBOHYDRATE BINDING; 15 CARBOHYDRATE BINDING AGENTS: POTENTIAL THERAPEUTICS WITH MULTIPLE INHIBITORY ACTIONS AGAINST ENVELOPED VIRUSES; 16 INFORMATICS FOR GLYCOBIOLOGY AND GLYCOMICS; INDEX
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- ISBN:
- 9786613227881
- 9781283227889
- 1283227886
- 9781118017579
- 1118017579
- 9781118017586
- 1118017587
- 9781118017562
- 1118017560
- OCLC:
- 746321025
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