Mammalian cell biotechnology in protein production / editors, Hansjörg Hauser, Roland Wagner.

Format:

Book

Contributor:

Hauser, Hansjörg, 1949-

Wagner, Roland, 1956-

Language:

English

Subjects (All):

Proteins--Biotechnology.

Proteins.

Animal cell biotechnology.

Mammals--Cytology.

Mammals.

Physical Description:

1 online resource (512 p.)

Edition:

1st ed.

Place of Publication:

Berlin ; New York : Walter de Gruyter, 1997.

Language Note:

English

Summary:

"Hauser and Wagner have presented the new possibilities of Mammalian Cell Biology in a very informative and stimulating manner." Prof. Dr. Hans Fritz, Ludwig-Maximilians-University Munich

"Hauser und Wagner haben die neuen Möglichkeiten der Mammalian Cell Biology sehr anregend dargestellt."Prof. Dr. Hans Fritz, Ludwig-Maximilians-Universität München

Contents:

Frontmatter

Preface

Contents

Contributors List

1. Genetic Manipulation of Mammalian Cells

1.1 Heterologous Expression of Genes in Mammalian Cells / Hauser, Hansjörg

1.2 Permanent Gene Expression in Mammalian Cells: Gene Transfer And Selection / Schlokat, Uwe / Himmelspach, Michèle / Falkner, Falko G. / Dorner, Friedrich

1.3 Vectors for Gene Transfer and Expression in Animal Cells / Sandig, Volker / Lieber, Andre / Strauss, Michael

1.4 Aspects of Gene Transfer and Gene Amplification in Recombinant Mammalian Cells / Wurm, Florian Μ.

1.5 Isolation of Recombinant Cell Clones Exhibiting High-Level Expression of the Introduced Gene / Wirth, Manfred

1.6 Genetic Engineering of Antibodies and Derivatives from Mammalian Cells / Schäffner, Michaela / Kaluza, Brigitte / Weidle, Ulrich Η.

1.7 Safety Evaluation of Products Derived From Mammalian Cell Lines / Onions, David

2. Biological Aspects of Animal Cells

2.1 Metabolic Control of Animal Cell Culture Processes / Wagner, Roland

2.2 Glycosylation: A Post-Translational Modification / Savage, Angela

3. Cell Cultivation Technology

3.1 Bioreactors Designed for Animal Cells / Tokashiki, Michiyuki / Yokoyama, Seiichi

3.2 Hydrodynamic Properties in Bioreactors / Chattopadhyay, Devamita / Garcia-Briones, Miguel / Venkat, Raghavan / Chalmers, Jeffrey J.

3.3 Kinetics and Simulation of Animal Cell Processes / Goergen, Jean-Louis / Marc, Annie / Engasser, Jean-Marc

3.4 On-line and Off-line Process Analysis / Scheper, Thomas / Freitag, Ruth / Scrienc, Friedrich

4. Down-Stream Processing

4.1 Principles of Product Extraction from Cell Culture and Purification for Pharmaceutical Proteins / Jungbauer, Alois

4.2 Validation of Downstream Processes / Walter, Joachim / Allgaier, Hermann

Index

Backmatter

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographical references and index.

ISBN:

9783110809282

3110809281

OCLC:

607788650