Spacecraft maximum allowable concentrations for selected airborne contaminants. Volume 1 / Subcommittee on Spacecraft Maximum Allowable Concentrations, Committee on Toxicology, Board on Environmental Studies and Toxicology, Commission on Life Sciences, National Research Council.

Format:

Book

Author/Creator:

National Research Council (U.S.). Subcommittee on Spacecraft Maximum Allowable Concentrations.

Language:

English

Subjects (All):

Space cabin atmospheres.

Space vehicles--Air pollution.

Space vehicles.

Space vehicles--Air quality--Standards.

Space vehicles--Contamination.

Space vehicles--Environmental aspects.

Toxicology--Research--United States.

Toxicology.

Physical Description:

1 online resource (235 p.)

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academy Press, 1994.

Language Note:

English

Contents:

""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""Copyright""; ""Preface""; ""Contents""; ""Spacecraft Maximum Allowable Concentrations for Selected Airborne Contaminants""; ""INTRODUCTION""; ""SUMMARY OF REPORT ON GUIDELINES FOR DEVELOPING SMACS""; ""REVIEW OF SMAC REPORTS""; ""REFERENCES""; ""Appendix A Executive Summary of Guidelines for Developing Spacecraft Maximum Allowable Concentration for Space Station�""; ""EXECUTIVE SUMMARY: SPACECRAFT MAXIMUM ALLOWABLE CONCENTRATIONS FOR SPACE STATION CONTAMINANTS""

""ENVIRONMENTAL CONTROL AND LIFE-SUPPORT SYSTEM""""MODIFICATION OF CONTAMINANT TOXICITY BY ENVIRONMENTAL FACTORS""; ""SOURCES AND TYPES OF DATA FOR ESTABLISHMENT OF SMACS""; ""Chemical-Physical Characteristics of Toxicants""; ""In Vitro Toxicity Studies""; ""Animal Toxicity Studies""; ""Clinical and Epidemiological Observations""; ""Pharmacokinetics and Metabolism""; ""Biological Markers""; ""RISK ASSESSMENT (DEVELOPMENT OF EXPOSURE CRITERIA)""; ""ISSUES IN MAKING RECOMMENDATIONS FOR THE ESTABLISHMENT OF SMACS""

""Appendix B Reports on Spacecraft Maximum Allowable Concentrations (SMACs) for Selected Airborne Contaminants""""B1 ACETALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Mucosal Irritation""; ""Miscellaneous Mucosal Effects""; ""Lethality""; ""Subchronic and Chronic Toxicity""; ""Nasal Toxicity""; ""Pulmonary and Renal Toxicity""; ""Carcinogenicity""; ""Genotoxicity""; ""Reproductive and Developmental Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""Carcinogenicity""

""Mucosal Irritation""""The Establishment of SMACs""; ""REFERENCES""; ""B2 AMMONIA""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Mechanisms of Tissue Injuries""; ""Mucosal Irritation in Naive Subjects""; ""Mucosal Irritation in Adapted Subjects""; ""Mucosal Irritation in Subjects Of Unknown Adaptation Status""; ""Toxic Effects of Massive Exposures""; ""Animal Models of Ammonia's Respiratory Damage""; ""Metabolic Acidosis""; ""RATIONALE""; ""1-h SMAC and 24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC""

""REFERENCES""""B3 CARBON MONOXIDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS""; ""TOXICITY SUMMARY""; ""Acute Toxicity""; ""Adaptation""; ""Subchronic and Chronic Toxicity""; ""Synergistic Effects""; ""RATIONALE""; ""1-h SMAC""; ""24-h SMAC""; ""7-d SMAC""; ""30-d SMAC and 180-d SMAC""; ""1-h and 24-h SMACs Immediately Following CO Exposure""; ""REFERENCES""; ""B4 FORMALDEHYDE""; ""PHYSICAL AND CHEMICAL PROPERTIES""; ""OCCURRENCE AND USE""; ""PHARMACOKINETICS AND METABOLISM""; ""TOXICITY SUMMARY""; ""Acute Toxicity""

""Subchronic and Chronic Toxicity""

Notes:

"The project was supported by the National Aeronautics and Space Administration grant no. NAGW-2239."

Includes bibliographical references.

OCLC:

58594839