Calcium binding proteins / Eugene A. Permyakov, Robert H. Kretsinger.

Format:

Book

Author/Creator:

Permiakov, E. A. (Evgenii Anatolevich)

Contributor:

Kretsinger, Robert H.

Series:

Wiley Series in Protein and Peptide Science

Wiley series in protein and peptide science

Language:

English

Subjects (All):

Calcium-binding proteins.

Calcium in the body.

Physical Description:

1 online resource (600 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, NJ : John Wiley & Sons, c2011.

Language Note:

English

Summary:

Calcium Binding Proteins explains the unique and highly diverse functions of calcium in biology, which are realized by calcium binding proteins. The structures and physical characteristics of these calcium binding proteins are described, as well as their functions and general patterns of their evolution. Techniques that underlie the description of proteins are discussed, including NMR, circular dichroism, optical rotatory dispersion spectroscopy, calorimetry,and crystallography. The book discusses the patterns of bochmical phenomena such as calcium homeostasis, mineralization, and cell

Contents:

CALCIUM BINDING PROTEINS; CONTENTS; Preface; 1 Historical Perspective; 1.1 Biomineralization; 1.2 Coagulation; 1.3 Secondary Messengers (Anticipated); 1.4 Colloids; 1.5 Cross-Linking and Cell Surfaces; 1.6 Secondary Messengers (Updated); 1.7 Pumps, Channels, and Ionophores; 1.8 Calcium Binding Proteins; 1.9 Secondary Messengers (Yet Again); 1.10 Mitochondria; 1.11 Pumps, Channels, and Ionophores; 1.12 Hormones; 1.13 Measurement; 1.14 Biomineralization: Redux; 2 Physiological Processes Involving Calcium Binding Proteins; 2.1 Calcium as a Secondary Messenger; 2.2 Calcium Buffers

2.3 Calcium Pumps and Channels2.4 Mitochondria; 2.5 Eubacteria; 2.6 Calcium and Extracellular Proteins; 2.7 Biomineralization; 2.8 Calcium and Viruses; 3 Comparison of the Ca2+ Ion with Other Metal Cations; 3.1 Calcium Isotopes; 3.2 Calcium in the Environment; 3.3 Uses of Calcium; 3.4 Health Effects of Calcium; 3.5 Biologically Significant Metals in the Periodic Table; 3.6 Hydration of Metal Ions; 3.7 "Hard" and "Soft" Metal Ions; 4 Complexes of Calcium and Other Cations with Compounds of Low Molecular Weight; 4.1 Crystal Structures of Complexes of Calcium with Low Molecular Weight Compounds

4.2 Dissociation Constants of Calcium and Analogs with Small Compounds4.3 Solubilities of Calcium and Analogs with Small Compounds; 5 Stoichiometry, Kinetics, and Thermodynamics of Calcium Binding; 5.1 Stoichiometry, Affinity, and Cooperativity of Binding; 5.2 Kinetics of Binding; 5.3 Partition of Free Energy of Binding (G) Among Enthalpy (H) and Entropy (S); 6 Experimental Methods Used to Study Calcium Binding to Proteins; 6.1 Radioactivity; 6.2 Ion-Selective Electrodes; 6.3 Calcium Buffers; 6.4 Dialysis, Equilibrium, and Flow; 6.5 Proteolysis; 6.6 Deuterium Exchange

6.7 Isothermal Titration Calorimetry6.8 Differential Scanning Calorimetry; 6.9 Mass Spectroscopy; 6.10 Calcium-Specific Dyes and Fluors; 6.11 Atomic Flame Absorption Spectroscopy; 6.12 Absorption Spectroscopy; 6.13 Fluorescence Spectroscopy; 6.14 Circular Dichroic and Optical Rotatory Dispersion Spectroscopy; 6.15 Nuclear Magnetic Resonance; 6.16 Electron Spin Resonance; 6.17 Surface Plasmon Resonance; 6.18 Extended X-ray Absorption Spectroscopy; 6.19 Small Angle X-ray Scattering; 6.20 Crystallography; 7 Structure and Evolution of Proteins; 7.1 Domain; 7.2 Structure; 7.3 Evolution

8 Protein Complexes with Metals Other than Calcium8.1 Essential Hard Cations; 8.2 Essential Metals with Several Valence States; 8.3 Conclusions; 9 Nonessential Metals; 9.1 Alkali Metals (Group Ia); 9.2 Alkali Earth Metals (Group IIa); 9.3 Group IIIa; 9.4 Group IVa; 9.5 Group Va; 9.6 Group VIIa; 9.7 Group VIII; 9.8 Group Ib; 9.9 Mercury (Group IIb); 9.10 Group IIIb; 9.11 Group IVb; 9.12 Group Vb; 9.13 Polonium (Group VIb); 9.14 Conclusions and Generalizations; 10 Parvalbumin; 10.1 Structure; 10.2 Function; 11 EF-Hand Proteins

11.1 CTER (Calmodulin, Troponin C, Essential and Regulatory Light Chain) Subfamily

Notes:

Description based upon print version of record.

Includes bibliographical references (p. 459-565) and index.

Description based on metadata supplied by the publisher and other sources.

ISBN:

9786613025012

9781118099544

1118099540

9781283025010

1283025019

9780470872383

0470872381

9780470872390

047087239X

OCLC:

689995803