COX-2 inhibitor research / Maynard J. Howardell, editor.

Format:

Book

Contributor:

Howardell, Maynard J.

Language:

English

Subjects (All):

Nonsteroidal anti-inflammatory agents.

Arthritis--Chemotherapy.

Arthritis.

Anti-inflammatory agents.

Physical Description:

1 online resource (263 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, c2006.

Language Note:

English

Summary:

COX-2 Inhibitors are newly developed drugs for inflammation that selectively block the COX-2 enzyme. Blocking this enzyme impedes the production of the chemical messengers (prostaglandins) that cause the pain and swelling of arthritis inflammation. Cox-2 inhibitors are a new class of nonsteroidal anti-inflammatory drugs (NSAIDS). Because they selectively block the Cox-2 enzyme and not the Cox-1 enzyme, these drugs are uniquely different from traditional NSAIDS. This new book explores new research in this field.

Contents:

Cyclooxygenase-2 inhibitor and gastric cancer / Yumin Li, Raaj K. Praseedom, and Andrew Butler et al.

Prevention and chemoprevention of gastric cancer : dietary habits, Helicobacter pylori and COX-2 inhibitors / Gerardo Nardone and Alba Rocco

Cyclooxygenases in cancer / Daniela Fodera ... et al.

Nephrotoxicity of nonsteroidal anti-inflammatory drugs : focus on selective cyclooxygenase-2 (COX-2) inhibitors / Steven G. Coca and Mark A. Perazella

Are COX-2 inhibitors active on intracellular oxidative processes? A study on in vitro and cellular models / Ange Mouithys-Mickalad et al.

Theoretical mechanism studies on dual inhibition of human cyclooxygenase-2 and 5-lipoxygenase by diaryl-pyrrolizine derivatives / R. Pouplana, C. Perez, and J. Ruiz

NSAIDs in animal models of Alzheimer's disease / N.G. Giovannini, C. Scali, and A. Bellucci

Relevance of COX-2 inhibitors in Alzheimer's disease / Amita Quadros, Laila Abdullah, and Nikunj Patel et al.

COX.1-COX.2 simultaneous inhibitory mechanism in gastric injury and COX.2-COX.3 in small intestine injury / Laudanno Oscar

Effects of COX-2 inhibitors on brain diseases / Takako Takemiya

Cyclooxygenase-2 overexpression and the chemopreventive and therapeutic uses of cyclooxygenase inhibitors in lung cancer / Zhongxing Liao et al.

Safety monitoring of celecoxib and rofecoxib in the New Zealand intensive medicines monitoring programme / David Coutler et al.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

1-61668-114-4

OCLC:

529875288