Lead generation approaches in drug discovery / [edited by] Zoran Rankovic, Richard Morphy.

Format:

Book

Contributor:

Ranković, Zoran.

Morphy, Richard.

Language:

English

Subjects (All):

Drug development.

Drugs--Design.

Drugs.

High throughput screening (Drug development).

Physical Description:

1 online resource (310 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, NJ : Wiley, c2010.

Language Note:

English

Summary:

An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to improve the chances of finding such a compound. Written by leading scientists and established opinion leaders from industry and academia, this book provides an authoritative overview of the field, as well as the theory, practice, and scope, of the principal Lead Generation Approaches in Dru

Contents:

LEAD GENERATION APPROACHES IN DRUG DISCOVERY; CONTENTS; PREFACE; CONTRIBUTORS; 1 Lead Discovery: The Process; 2 High Throughput Screening Approach to Lead Discovery; 3 In Silico Screening; 4 Fragment-Based Lead Discovery; 5 Design of Multitarget Ligands; 6 De novo Drug Design; 7 Role of Natural Products in Drug Discovery; 8 Early Screening for ADMET Properties; 9 Role of Chemistry in Lead Discovery; INDEX

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on metadata supplied by the publisher and other sources.

ISBN:

9786612687174

9781282687172

1282687174

9780470584170

0470584173

9780470584163

0470584165

OCLC:

609862512