Cerebral blood flow regulation / Nodar P. Mitagvaria and Haim I. Bicher.

Format:

Book

Author/Creator:

Mitagvariia, N. P. (Nodar Prokof'evich)

Contributor:

Bicher, Haim I.

Language:

English

Subjects (All):

Cerebral circulation--Regulation.

Cerebral circulation.

Brain--Blood-vessels.

Brain.

Physical Description:

1 online resource (229 p.)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, c2009.

Language Note:

English

Summary:

Studies of the mechanisms relating blood supply to the brain appeared to be, in some sense, at a deadlock. Despite extensive application of different methodical approaches, no qualitative progress has been observed in these studies at the present time. This is perhaps due to the traditional, but not understandable, separation of neurophysiological and "circulatory" studies. It may seem very paradoxical, but the study of cerebral blood circulation proceeds almost in complete isolation from the knowledge about brain functions and does not take into account the specificity of the working brain as a part of the whole body. This book comprehensively addresses the issues of blood flow regulation. It is well known that the brain belongs to the group of organs having a high level of oxygen consumption. Oxygen consumption by the brain is an average 4.6 ml per 100 g of tissue per minute. In humans, the level of oxygen consumption by the whole brain attains 46 ml/min. This makes up approximately 20% of the total oxygen volume consumed by the organism. Consequently, the cerebral tissue is characterised by highly energetic processes. There is evidence indicating that even in functionally resting conditions, 18% of the entire energy expenditure of the body is utilised by the brain Calculations made by Rushmer indicate that the intensity of energy consumption by the human brain appears to be on average 20 Watt.

Contents:

""CEREBRAL BLOOD FLOW REGULATION ""; ""CONTENTS ""; ""INTRODUCTION ""; ""SECTION 1: REGULATION OF LOCAL CEREBRAL BLOOD FLOW DURING SYSTEMIC ARTERIAL PRESSURE CHANGES ""; ""SOME THEORETICAL PREREQUISITES ""; ""1.1. HISTORICAL BACKGROUND ""; ""1.2. POSSIBLE REASONS FOR CONTROVERSIAL INTERPRETATIONS OF THE RESULTS IN THE STUDY OF AUTOREGULATION ""; ""MAIN THEORIES OF AUTOREGULATION OF CBF""; ""2.1. MYOGENIC THEORY ""; ""2.2. METABOLIC THEORY ""; ""2.3. NEUROGENIC THEORY OF AUTOREGULATION ""; ""ANALYSIS OF DYNAMIC CHARACTERISTICS OF LOCAL CBF AUTOREGULATION ""

""3.1. ANALYSIS OF THE DYNAMIC CHARACTERISTICS OF LOCAL CBF AUTOREGULATION IN CASE OF SHORT-LASTING SAP CHANGES """"STRUCTURAL ORGANIZATION IN THE BRAIN BLOOD SUPPLY AUTOREGULATION ""; ""SECTION 2: REGULATION OF LOCAL CEREBRAL BLOOD FLOW DURING OXYGEN INSUFFICIENCY ""; ""SOME THEORETICAL PREREQUISITES""; ""5.1. HISTORICAL BACKGROUND ""; ""5.2. THE HOMEOSTATIC RANGE OF CBF AND ITS ROLE IN HETEROGENITY OF CBF RESPONSES DURING HYPOXIA""; ""DYNAMIC CHARACTERISTICS OF REGULATION OF LOCAL BLOOD FLOW IN THE CEREBRAL CORTEX UNDER CONDITIONS OF HYPOXIA, ANOXIA AND ASPHYXIA ""

""SECTION 3: REGULATION OF LOCAL BLOOD FLOW IN THE BRAIN DURING CHANGES IN ITS FUNCTIONAL-METABOLIC ACTIVITY """"GENERAL PROBLEMS OF THE BRAIN FUNCTIONAL ACTIVITY AND LOCAL BLOOD FLOW COUPLING ""; ""7.1. BLOOD SUPPLY TO THE CORTEX OF ""NONWORKING"" BRAIN ""; ""7.2. THE LOCAL BLOOD FLOW COUPLING WITH THE CORTICAL ELECTRICAL ACTIVITY ""; ""7.3. BLOOD FLOW IN THE CORTEX DURING SENSORY STIMULATION ""; ""7.4. BLOOD FLOW IN THE CORTEX DURING MOTOR ACTIVITY ""; ""7.5. BLOOD FLOW IN THE CORTEX DURING MENTAL ACTIVITY ""; ""7.6. BLOOD FLOW IN THE CORTEX DURING EMOTIONAL REACTIONS ""

""DYNAMIC CHARACTERISTICS OF LOCAL BLOOD FLOW REGULATION IN DIFFERENT BRAIN STRUCTURES DURING PERFORMANCE OF BEHAVIORAL ACTS""""8.1. CHOICE OF THE EXPERIMENTAL CONDITIONS ""; ""8.2. REDISTRIBUTION OF LOCAL BLOOD FLOW IN DIFFERENT CORTICAL AREAS DURING MAZE TASK SOLUTION ""; ""8.3. POSSIBLE MECHANISMS OF THE CORTICAL BLOOD FLOW RESPONSES DURING FUNCTIONAL LOADS ""; ""8.4. DYNAMICS OF LCBF IN THE RAT'S CEREBRAL CORTEX FOLLOWING INJECTION OF ANTICHOLINERGIC DRUGS ""; ""DYNAMICS OF LOCAL BLOOD FLOW AND OXYGEN TENSION IN THE BRAIN IN DIFFERENT PHASES OF THE SLEEP-WAKING CYCLE ""

""9.1. HISTORICAL BACKGROUND """"9.2. LOCAL BLOOD FLOW AND PO2 CHANGES IN THE DORSAL HIPPOCAMPUS AND SENSORIMOTOR CORTEX DURING SLEEP-WAKEFULNESS CYCLE ""; ""SECTION 4: CEREBRAL BLOOD FLOW, OXYGEN SUPPLY, AND MORPHOLOGICAL CHANGES INDUCED BY LOCAL HYPERTHERMIA ""; ""DYNAMICS OF LOCAL CEREBRAL BLOOD FLOW DURING MICROWAVE RADIATION ""; ""10.1. EXPERIMENTAL AND CLINICAL STUDY OF MICROWAVE RADIATION ""; ""10.2. DYNAMIC CHARACTERISTICS OF THE REGULATION OF LCBF DURING LOCAL MICROWAVE RADIATION OF THE BRAIN ""

""PHYSIOLOGICAL AND MORPHOLOGICAL CHANGES IN CEREBRAL TISSUE, CAUSED BY HYPERTHERMIA-INDUCED THROMBOSIS OF THE CEREBRAL VESSELS ""

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

1-60741-405-8

OCLC:

430021281