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Methodological challenges in biomedical HIV prevention trials / Committee on the Methodological Challenges in HIV Prevention Trials, Board on Global Health ; Stephen W. Lagakos and Alicia R. Gable, editors ; Institute of Medicine of the National Academies.

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National Academies Press Available online

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Format:
Book
Contributor:
Gable, Alicia.
Lagakos, Stephen W.
Institute of Medicine (U.S.). Board on Global Health.
Institute of Medicine (U.S.). Committee on the Methodological Challenges in HIV Prevention Trials.
National Academies (U.S.)
Language:
English
Subjects (All):
AIDS (Disease)--Prevention.
AIDS (Disease).
Internal medicine.
Physical Description:
1 online resource (270 p.)
Edition:
1st ed.
Place of Publication:
Washington, D.C. : National Academies Press, c2008.
Language Note:
English
Summary:
"This IOM committee was formed at the request of the Bill & Melinda Gates Foundation and charged with addressing methodological challenges in late-stage nonvaccine biomedical HIV prevention trials with a specific focus on microbicide and pre-exposure prophylaxis trials."
Contents:
""Front Matter""; ""Reviewers""; ""Contents""; ""Summary""; ""Introduction""; ""1 The Status and Challenges of Biomedical HIV Prevention Trials""; ""2 Basic Design Features: Size, Duration, and Type of Trials, and Choice of Control Group""; ""3 Design Considerations: Risk-Reduction Counseling""; ""4 Design Considerations: Pregnancy""; ""5 Design Considerations: Adherence""; ""6 Design Considerations: Recruitment and Retention""; ""7 Site Preparedness""; ""8 Estimating HIV Incidence""; ""9 Interim Monitoring and Analysis of Results""; ""10 Alternative Designs""; ""Appendixes""
""Appendix A: Public Committee Meeting Agendas""""Appendix B: Acronyms""; ""Appendix C: Supporting Materials for Chapter 2""; ""Appendix D: Methods for Analyzing Adherence""; ""Appendix E: Committee Biographies""
Notes:
Description based upon print version of record.
Includes bibliographical references.
ISBN:
9786611767471
9780309177795
0309177790
9781281767479
1281767476
9780309114318
0309114314
OCLC:
923278309

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