Preimplantation genetic diagnosis / edited by Joyce Harper.

Format:

Book

Contributor:

Harper, Joyce C., editor.

Language:

English

Subjects (All):

Preimplantation genetic diagnosis.

Physical Description:

1 online resource (viii, 294 pages) : digital, PDF file(s).

Edition:

Second edition.

Place of Publication:

Cambridge : Cambridge University Press, 2009.

Language Note:

English

Summary:

Preimplantation genetic diagnosis (PGD) is a key technique in modern reproductive medicine. Originally developed to help couples who were at risk of transmitting single-gene genetic abnormalities to their children, the development of the FISH technique broadened chromosome analysis to include detection of more complex inherited abnormalities. The last decade has seen the development of aneuploidy screening (PGS) for infertile couples, using the same techniques as PGD but screening for as many chromosomes as possible. PGD has always been a controversial procedure and embryo manipulation and selection is still illegal in some countries. The second edition of this leading textbook describes all aspects of PGD, with chapters written by key international experts in the field. A must for anyone interested in learning more about PGD, it will be of interest to everyone working in the fields of IVF, genetic diagnosis, genetic counselling, and prenatal diagnosis - including clinicians, embryologists, nurses, and clinical scientists.

Contents:

Introduction to preimplantation genetic diagnosis / Joyce Harper

Assisted reproductive technologies / Joyce Harper, Alpesh Doshi, and Paul Serhal

Genetic basis of inherited disease / Joep Geraedts and Joy Delhanty

Genetic counselling / Alison Lashwood

Prenatal screening and diagnosis / Anna L. David and Charles H. Rodeck

Preimplantation embryo development / Kay Elder

Preimplantation genetics / Joy Delhanty and Dagan Wells

Clinical aspects of preimplantation genetic diagnosis / Christine de Die-Smulders, Maartje van Rij, and Johannes Evers

Polar body biopsy techniques / Markus Montag, Katrin van der Ven, and Hans van der Ven

Cleavage-stage embryo biopsy / Anick De Vos

Lastocyst biopsy / Monica Parriego, Francesca Vidal, and Anna Veiga

Preimplantation genetic diagnosis for chromosome rearrangements / Caroline Mackie Ogilvie and Paul N. Scriven

Preimplantation genetic diagnosis for infertility (PGS) / Santiago Munné

Preimplantation genetic diagnosis for sex-linked diseases and sex-selection for non-medical reasons / Caroline Mackie Ogilvie and Paul N. Scriven

Preimplantation genetic diagnosis for monogenic disorders : multiplex PCR and whole-genome amplification for gene analysis at the single cell level / Karen Sermon

Quality control and quality assurance in preimplantation genetic diagnosis / Alan Thornhill and Sjoerd Repping

Preimplantation genetic testing : normative reflections / Guido de Wert

Preimplantation genetic diagnosis : the future / Leeanda Wilton.

Notes:

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Includes bibliographical references and index.

ISBN:

1-107-20038-5

1-282-15573-3

9786612155734

0-511-54059-0

0-511-54093-0

0-511-53931-2

0-511-53848-0

0-511-58157-2

0-511-54015-9

OCLC:

609840600