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Principles and practice of the biologic therapy of cancer / edited by Steven A. Rosenberg ; Stephanie Harris, developmental editor ; Mary Ann McLaughlin, supervising editor ; Mark Lerner, cover designer.
- Format:
- Book
- Language:
- English
- Subjects (All):
- Biological response modifiers--Therapeutic use.
- Biological response modifiers.
- Cancer--Immunotherapy.
- Cancer.
- Cancer--Gene therapy.
- Physical Description:
- 1 online resource (955 p.)
- Edition:
- Third edition.
- Place of Publication:
- Philadelphia, Pennsylvania : Lippincott Williams & Wilkins, 2000.
- Language Note:
- English
- Summary:
- This reference on the biologic therapy of cancer provides scientific and practical information to both researchers and clinicians involved in the development and application of new cancer treatments. Major sections of the book cover: cytokines; cell transfer therapy; monoclonal antibodies; cancer vaccines; gene therapy; and antiangiogenesis therapy. Each section begins with basic principles and preclinical studies, and proceeds to clinical applications. The clinical chapters present comprehensive analyses of clinical data, emphasizing the indications for treatment and the practical guidelines necessary to safely apply these new approaches.
- Contents:
- Cover
- Copyright
- Authors
- Preface
- Contents
- Section I Principles and Practice of Cytokine Therapy
- 1 Interleukins: Overview
- 2 Interleukin-2: Preclinical Trials
- 3 Interleukin-2: Clinical Applications
- 4 Interleukin-2: Clinical Applications
- 5 Interleukin-12: Clinical Applications Hideaki Tahara
- 6 Colony-Stimulating Factors: Basic Principles and Preclinical Studies
- 7 Colony-Stimulating Factors: Clinical Applications
- 8 Tumor Necrosis Factor: Basic Principles and Clinical Applications in Systemic and Regional Cancer Treatment
- 9 Interferon-α and -β: Basic Principles and Preclinical Studies
- 10 Interferon-α and -β: Clinical Applications
- 11 Interferon-γ: Basic Principles and Clinical Applications
- Section II Principles and Practice of Cell Transfer Therapy
- 12 Cell Transfer Therapy: Basic Principles and Preclinical Studies
- 13 Cell Transfer Therapy: Clinical Applications
- Section III Principles and Practice of Monoclonal Antibody Therapy
- 14 Monoclonal Antibodies: Basic Principles
- 15 Monoclonal Antibodies: Clinical Applications
- Section IV Principles and Practice of Cancer Vaccines
- 16 Cancer Vaccines: Cancer Antigens
- 17 Cancer Vaccines: Basic Principles
- 18 Cancer Vaccines: Clinical Applications
- Section V Principles and Practice of Gene Therapy
- 19 Basic Principles of Gene Therapy
- 20 Gene Therapy: Clinical Applications
- 21 Antiangiogenesis: Basic Principles and Preclinical Models
- 22 Antiangiogenesis: Clinical Applications
- 23 Delivery of Biologic Molecules and Cells to Tumors
- 24 Flt-3 and Flt-3 Ligand
- 25 CTLA-4 Blockade in Tumor Immunotherapy
- Index.
- Notes:
- Includes index.
- Description based on print version record.
- ISBN:
- 1-4698-7456-3
- OCLC:
- 48809870
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