Coupled bioluminescent assays : methods, evaluations, and applications / Michael J. Corey.

Format:

Book

Author/Creator:

Corey, Michael J. (Michael James), 1953-

Language:

English

Subjects (All):

Bioluminescence assay.

Physical Description:

1 online resource (326 p.)

Edition:

1st ed.

Place of Publication:

Hoboken, N.J. : Wiley, c2009.

Language Note:

English

Summary:

This book highlights the applications of coupled bioluminescence assay techniques to real-world problems in drug discovery, environmental and chemical analysis, and biodefense. It separates theoretical aspects from the applied sections in a clear and readable way. Coupled Bioluminescent Assays, explains the uses of CB technologies across drug discovery to analyze toxicity, drug receptors, and enzymes. It covers applications in environmental analysis and biodefense, including cytotoxicity, fertilizer and explosives analysis, and nerve agent and pesticide detection. This is the premier reference

Contents:

Introduction

Coupled bioluminescent reactions in practice

Coupled bioluminescent cytotoxicity assays

The role of coupled bioluminescent assays in kinase screening and study

Coupled bioluminescent phosphatase assays

Acetylcholinesterase

Measurement of nitric oxide synthase activity by coupled bioluminescence

The coupled bioluminescent pyrophosphorolysis assay

Coupled luminescent assays of G-protein-coupled receptors

Coupled bioluminescent protease assays

Coupled luminescent assays involving aequorin

Coupled bioluminescent reporter assays

Coupled bioluminescent assays : regulatory concerns

Coupled bioluminescent determination of bioburden and sterility

Environmental applications of coupled bioluminescent assays.

Notes:

Description based upon print version of record.

Includes bibliographical references (p. 265-289) and index.

Description based on metadata supplied by the publisher and other sources.

ISBN:

9786611939038

9781281939036

128193903X

9780470422465

0470422467

9780470422458

0470422459

OCLC:

299043648