Neurobiology of obesity / [edited by] Jenni Harvey, Dominic J. Withers.

Format:

Book

Contributor:

Harvey, Jenni.

Withers, Dominic John.

Language:

English

Subjects (All):

Obesity--Etiology.

Obesity.

Obesity--Pathophysiology.

Physical Description:

1 online resource (xii, 324 pages) : digital, PDF file(s).

Edition:

1st ed.

Place of Publication:

Cambridge : Cambridge University Press, 2008.

Language Note:

English

Summary:

Obesity is one of the prime contributors to ill health in modern society, affecting around 20-25% of the population. It can cause or exacerbate a variety of health problems and is often associated with several other diseases including type II diabetes, coronary heart disease and certain types of cancer. Significant progress has been made in understanding the role of the nervous system and, in particular, the complex interplay between a range of orexigenic and anorectic agents within specific hypothalamic nuclei in the regulation of energy balance, appetite and adiposity. Several different neuronal pathways, neurotransmitters and hormones have been identified as major players in the regulation of feeding behavior and body weight and these are now being targeted as having therapeutic potential. Written for academic researchers and graduate students, Neurobiology of Obesity is a concise overview of recent developments in this field, written by leading international experts.

Contents:

Introductory chapter / Benjamin C.T. Field, Caroline J. Small and Stephen R. Bloom

Genetics of human and rodent body weight regulation / Karine Clément

Hypothalamic control of energy homeostasis / Neel S. Singhal and Rexford S. Ahima

Leptin and insulin as adiposity signals / Kevin D. Niswender

Convergence of leptin and insulin signaling networks in obesity / Calum Sutherland and Mike Ashford

Diet-induced obesity in animal models and what they tell us about human obesity / Barry E. Levin and Alison M. Strack

Melanocortins and the control of body weight / Virginie Tolle and Malcolm J. Low

Role of opiate peptides in regulating energy balance / Richard J. Bodnar and Allen S. Levine

Ghrelin : an orexigenic signal from the stomach / Tamas Horvath

Central nervous system controls of adipose tissue apoptosis / Mary Anne Della-Fera, Mark W. Hamrick and Clifton A. Baile

Potential therapies to limit obesity / Jason C.G. Halford.

Notes:

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Includes bibliographical references and index.

ISBN:

1-107-17776-6

1-281-94460-2

9786611944605

0-511-45597-6

0-511-45419-8

0-511-45727-8

0-511-54164-3

0-511-45325-6

0-511-45523-2

OCLC:

437240840