Genome sequencing technology and algorithms / Sun Kim, Haixu Tang, Elaine R. Mardis, editors.

Format:

Book

Contributor:

Kim, Sun, 1962-

Mardis, Elaine, 1962-

Tang, Haixu.

Language:

English

Subjects (All):

Genomes--Analysis.

Genomes.

Nucleotide sequence.

Physical Description:

1 online resource (275 p.)

Edition:

1st ed.

Place of Publication:

Boston : Artech House, c2008.

Language Note:

English

System Details:

data file

Summary:

"From a who's who of pioneers in the field comes a unique resource covering the latest advances in next generation genome sequencing and assembly. This groundbreaking book includes non-conventional techniques that are paving the way to potential new biomedical applications. Practitioners find unparalleled access to state-of-the-art DNA sequencing technologies, new algorithmic sequence assembly techniques, and emerging methods for both resequencing and de novo genome analysis, which all together offer the most solid foundation possible for tackling the full range of experimental and computational challenges in the genome sciences today."--Jacket.

Contents:

An overview of new DNA sequencing technology

Array-based pyrosequencing technology

The role of resequencing arrays in revolutionizing DNA sequencing

Polony sequencing

Genome sequencing: a complex path to personalized medicine

Overview of genome assembly techniques

Fragment assembly algorithms

Assembly for double-ended short read sequencing technologies

Genome characterization in the post-human genome project era

The haplotyping problem: an overview of computational models and solutions

Analysis of genomic alterations in cancer

High-throughput assessments of epigenomics in human disease

Comparative sequencing, assembly, and anchoring.

Notes:

Description based upon print version of record.

Print version record.

Includes bibliographical references and index.

ISBN:

1-59693-095-0

OCLC:

437208196