Organophosphates and health / editors, Lakshman Karalliedde ... [et al.].

Format:

Book

Contributor:

Karalliedde, Lakshman.

Language:

English

Subjects (All):

Organophosphorus compounds--Toxicology.

Organophosphorus compounds.

Toxicology.

Physical Description:

1 online resource (512 p.)

Edition:

1st ed.

Place of Publication:

London : Imperial College Press ; Singapore ; River Edge, NJ : Distributed by World Scientific Pub. Co., c2001.

Language Note:

English

Summary:

Few chemical compounds created by man have caused greater controversy than organophosphates. Conceived as insecticides, they have also been developed to become the most feared of chemical weapons. The control of vectors of diseases from which millions die or are disabled is heavily dependent on organophosphates, as are efforts to maintain food production in the face of uncontrolled population growth, diminishing arable land and the possibility of global warming. As the toxicity of organophosphates is non-specific, it has caused ill health and death in man, and has contributed to adverse ecolo

Contents:

CONTENTS ; Preface ; Acknowledgements ; List of Contributors ; Abbreviations ; Introduction ; 1. Organophosphates: History Chemistry Pharmacology ; 1.1. INTRODUCTION ; 1.2. HISTORY ; 1.3. STRUCTURE AND NOMENCLATURE OF ORGANOPHOSPHATE ANTI ChEs ; 1.4. EFFECTS OF OPs

1.5. OPS USED FOR PROPERTIES OTHER THAN ANTIChE ACTIVITY. References ; 2. Socio-Economics Health Issues and Pesticides ; 2.1. Introduction ; 2.2. Role in Control of Vector Borne Diseases ; 2.3. Role in Food Production and Storage ; 2.4. Pesticide-Associated Human Ill-Health

2.5. Effects on the Environment and Wild Life 2.6. Insecticide-Related Disease and Global Health Priorities ; 2.7. Role of Industry ; 2.8. Environmental Changes: Effect on Food and Disease ; 2.9. Alternatives ; 2.10. Conclusions ; Acknowledgements ; Other sources of information

Thanks 3. Factors Influencing Organophosphate Toxicity in Humans ; 3.1. Introduction ; 3.2. Route of Exposure and Absorption ; 3.3. Dose ; 3.4. Distribution ; 3.5. Metabolism ; 3.6. Tissue binding ; 3.7. Elimination ; 3.8. Alterations in Metabolism ; 3.9. Racemic Mixtures

3.10. Concluding Remarks References ; 4. Organophosphorus Chemical Warfare Agents ; 4.1. Introduction ; 4.2. Physical properties ; 4.3. Toxicology ; 4.4. General Toxicity ; 4.5. Effects of Subchronic or Longterm Exposure to Nerve Agents ; 5. Diagnosis ; 6. Treatment

7. Prophylaxis of nerve agent poisoning

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9786611865993

9781281865991

1281865990

9781848161443

1848161441

OCLC:

815741826