Proton radiotherapy accelerators / Wioletta Wieszczycka, Waldemar H. Scharf.

Format:

Book

Author/Creator:

Wieszczycka, Wioletta.

Contributor:

Scharf, Waldemar.

Language:

English

Subjects (All):

Proton accelerators.

Radiotherapy, High energy--Equipment and supplies.

Radiotherapy, High energy.

Particles (Nuclear physics).

Physical Description:

1 online resource (342 p.)

Edition:

1st ed.

Place of Publication:

River Edge, NJ : World Scientific, c2001.

Language Note:

English

Summary:

Hadronic radiotherapy uses particle beams to treat tumors located near critical body structures and tumors that respond poorly to conventional photon and electron beam radiotherapy. Initial research in hadronic radiotherapy was performed using accelerators built for physics research. The good results of the proton and ion therapy programs have enhanced the tendency to use protontherapy as a routine method. There are about 20 working protontherapy facilities (first, second and third generation) and more than 30 centers are planned. This book presents the first comprehensive overview of the fi

Contents:

CONTENTS ; PREFACE ; CHAPTER 1 INTRODUCTION ; 1.1 Cancer and Radiation Therapy ; 1.2 Historical Development of Radiation Therapy ; 1.3 Modern Tools for Conventional Radiotherapy ; 1.3.1 Main Parameters of Conventional Therapy Beams ; 1.3.2 Elements of Conventional Accelerator System

1.3.3 Reasons for Development of Non-conventional Radiotherapies1.4 Glossary ; 1.4.1 Beam Intensity ; 1.4.2 Beam Range in an Absorbing Medium ; 1.4.3 Bragg Peak Modulation ; 1.4.4 Range Adjustment ; 1.4.5 Radiation Field ; 1.4.6 Field Homogeneity on a Transverse Section

1.4.7 Homogeneity Region in a Plane Orthogonal to the Beam Direction 1.4.8 Field Homogeneity along the Beam Axis ; 1.4.9 Field Symmetry ; 1.4.10 Lateral Penumbra ; 1.4.11 Distal Dose Fall-off ; CHAPTER 2 PHYSICAL AND RADIOBIOLOGICAL PROPERTIES OF HADRONS

2.1 Basic Facts in Radiotherapy 2.1.1 Dose-Effects Curves ; 2.1.2 RBE Dependence on LET and OER ; 2.2 An Introduction to Hadrontherapy ; 2.3 Energy Loss ; 2.3.1 Nuclear Energy Loss ; 2.3.2 Electronic Energy Loss ; 2.3.3 Range and Bragg Curves

2.3.4 Track Formation and Radial Dose Distribution 2.4 Interaction of Hadrons with Biological Matter ; 2.4.1 Cellular Organization and the Target of Radiation Action ; 2.4.2 Hadrons' Track in Biological Matter ; 2.4.3 RBE of Hadrons ; 2.4.4 Fractionation and Oxygen Effect

CHAPTER 3 STATUS OF CLINICAL RESEARCH IN PROTONTHERAPY

Notes:

Description based upon print version of record.

Includes bibliographical references (p. 307-317) and index.

ISBN:

9786611960667

9781281960665

1281960667

9789812811646

9812811648

OCLC:

815756561