Endothelial dysfunctions and vascular disease / edited by Raffaele De Caterina, Peter Libby ; foreword by Michael A. Gimbrone Jr.

Format:

Book

Contributor:

De Caterina, R., 1954-

Libby, Peter.

Language:

English

Subjects (All):

Blood-vessels--Pathophysiology.

Blood-vessels.

Vascular endothelium.

Physical Description:

1 online resource (432 p.)

Edition:

1st ed.

Place of Publication:

Malden, MA : Blackwell Futura, 2007.

Language Note:

English

Summary:

Bridging the gap between the laboratory and the bedside, this timely volume illuminates the connection between endothelial dysfunction and vascular disease. This comprehensive survey of atherosclerotic disease begins with biology - incorporating the latest breakthroughs in the field - then elucidates risk factors and diagnostic tools and markers. A major section on endothelium-directed prevention and therapy shows you how to apply cutting-edge research to clinical care. Under the careful editorial guidance of Drs. De Caterina and Libby, the highly-regarded contributors address:- endothel

Contents:

Endothelial Dysfunctions and Vascular Disease; Contents; Contributors; Preface; Foreword; Acknowledgments; Dedication; Part I: The basis of endothelial involvement in vascular diseases; 1 Endothelial functions and dysfunctions; 2 Endothelial activation and the initiation of atherosclerosis; 3 Mechanisms of plaque progression and complications; 4 Angiogenesis in cardiovascular disease; Part II: The endothelium and cardiovascular risk factors; 5 VLDL and atherosclerosis; 6 High-density lipoprotein and atheroprotection

7 Advanced glycation endproducts and the accelerated atherosclerosis in diabetes8 Homocysteine and endothelial dysfunction; 9 Lipoprotein(a) and the artery wall; 10 Oxidative stress and vascular disease; 11 Infections and vascular disease; Part III: Diagnostic tools and markers of endothelial functions; 12 Endothelial vasodilatory dysfunction: basic concepts and practical implementation; 13 Endothelial vasodilatory dysfunction and risk factors in adults; 14 Endothelial vasodilatory dysfunction in early life; 15 Endothelial vasodilatory dysfunction in hypertension

16 Vascular function and diabetes mellitus17 Dyslipidemia and endothelial dysfunction: pathophysiology and therapy; 18 Soluble adhesion molecules as in vivo biohumoral markers of vascular cell activation; Part IV: Endothelium-directed prevention and therapy; 19 Hormone replacement therapy and cardiovascular disease; 20 Anti-atherogenic effects of omega-3 fatty acids; 21 Treatment of endothelial dysfunction and atherosclerosis by cholesterol lowering; 22 Antioxidants and endothelial protection

23 Angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers to reverse endothelial dysfunction24 PPARs in atherosclerosis; 25 Stem cells in atherosclerosis and atherosclerosisrelated vascular disorders; 26 Endothelium-targeted gene and cell-based therapy for cardiovascular disease; Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

9786611320119

9781281320117

1281320110

9780470984819

0470984813

9780470988473

0470988479

9780470994092

0470994096

OCLC:

476170608