Blood disorders in the elderly / edited by Lodovico Balducci, William Ershler, Giovanni de Gaetano.

Format:

Book

Contributor:

Balducci, Lodovico, editor.

Ershler, William B., editor.

De Gaetano, Giovanni, editor.

Language:

English

Subjects (All):

Blood--Diseases.

Blood.

Geriatrics.

Physical Description:

1 online resource (xii, 484 pages) : digital, PDF file(s).

Edition:

1st ed.

Place of Publication:

Cambridge : Cambridge University Press, 2008.

Language Note:

English

Summary:

The developed world has an increasingly aging population, with approximately 10% of the population aged over 65 years. As the incidence and prevalence of blood disorders increases with age, these conditions are a heavy burden on healthcare systems. Blood Disorders in the Elderly will provide hematologists, geriatricians and all clinicians involved in the care of patients with blood disorders with clear clinical advice on the diagnosis and management of these conditions. The introductory section reviews epidemiology of aging and anemia and provides a comprehensive approach to the management of cancer in the aging patient. This is followed by a full discussion of hemopoiesis and changes it undergoes in aging. The remaining sections cover the diagnosis and management of all major disorders: anemia, malignancy, coagulation and platelet disorders and hemophilia. A detailed chapter on antithrombotic therapies is also included.

Contents:

Cover; Half-title; Title; Copyright; Contents; List of contributors; Preface; PART I Epidemiology; 1 Epidemiology of aging; 2 Introduxtion Epidemiology of anemia in older adults; 3 Introduxtion Cancer in the older person: a comprehensive approach; 4 Introduxtion From fitness to frailty: toward a nosologic classification of the older aged person; PART II Hematopoiesis; 5 Stem cell exhaustion and aging; 6 Introduxtion Hematopoietic microenvironment and age; 7 Replicative senescence, aging, and cancer; 8 Qualitative changes of hematopoiesis; 9 Aging and hematopoietic stress

10 Introduxtion Immunoglobulin response and aging 11 Biological and clinical significance of monoclonal gammopathy; PART III Anemia of aging; 12 Erythropoietin and aging; 13 Iron and aging; 14 Prevalence and mechanisms of B12 deficiency; 15 Consequences of chronic anemia in the older person; 16 Introduxtion The pathogenesis of late-life anemia; 17 Treatment of late-life anemia; Part IV Hematologic malignancies and aging; 18 Cancer chemotherapy in the older person; 19 Introduxtion Acute myeloid leukemia in the elderly

20 Acute lymphoblastic leukemia in the elderly patient: diagnosis and therapy 21 Multiple myeloma; 22 Non-Hodgkin lymphoma; 23 Unusual lymphomas in the elderly; 24 Chronic lymphocytic leukemia in the elderly; 25 Polycythemia vera and idiopathic myelofibrosis in the elderly; PART V Disorders of hemostasis in the elderly; 26: Acquired hemophilia in the elderly; 27 Blood coagulation and aging; 28 Platelet disorders in the elderly; 29 Gene-environment interactions and vascular risk in the elderly; 30 Antithrombotic therapy: guidelines for the elderly; Index

Notes:

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Includes bibliographical references and index.

ISBN:

1-107-18225-5

1-281-24352-3

9786611243524

0-511-37809-2

0-511-37721-5

0-511-37627-8

0-511-37474-7

0-511-54523-1

0-511-37898-X

OCLC:

476127389