Evaluation of certain veterinary drug residues in food : sixty-sixth report of the Joint FAO/WHO Expert Committee on Food Additives.

Format:

Book

Author/Creator:

Joint FAO/WHO Expert Committee on Food Additives. Meeting (66th : 2006 : Rome, Italy)

Contributor:

World Health Organization.

Food and Agriculture Organization of the United Nations.

Series:

Technical report series (World Health Organization) ; 939.

WHO technical report series, 0512-3054 ; 939

Language:

English

Subjects (All):

Veterinary drug residues--Congresses.

Veterinary drug residues.

Food additives--Congresses.

Food additives.

Veterinary drugs--Congresses.

Veterinary drugs.

Food contamination--Congresses.

Food contamination.

Physical Description:

vi, 80 p.

Edition:

1st ed.

Other Title:

66th report of the Joint FAO/WHO Expert Committee on Food Additives

Sixty-sixth report of the Joint FAO/WHO Expert Committee on Food Additives

Place of Publication:

Geneva : World Health Organization, 2006.

Language Note:

English

Summary:

This report represents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in food and to recommend maximum levels for such residues in food. The first part of the report considers general principles regarding the evaluation of veterinary drugs within the terms of reference of JECFA, including compounds without an ADI or MRL; recommendations on principles and methods in derivation of MRLs, including a new procedure for estimating chronic dietary intakes; the use of a spreadsheet-based procedure for the statistical evaluation of residue depletion data; a revised approach for the derivation of microbiological ADIs; and the Committee's review of and comments on documents provided by the Codex Committee on Residues of Veterinary Drugs. Summaries follow of the Committee's evaluations of toxicological and residue data on a variety of veterinary drugs: three antimicrobial agents (colistin, erythromycin, flumequine), two production aids (melengestrol acetate, ractopamine hydrochloride, an insecticide (trichlorfon (metrifonate)), and an anthelminthic (triclabendazole). In addition, the attempt by the Committee to use tylosin as an example to investigate if evaluations are possible based on published data in the absence of data submissions from sponsors is described. Annexed to the report is a summary of the Committee's recommendations on these drugs, including acceptable daily intakes and proposed maximum residue limits.

Contents:

Intro

Contents

Introduction

General considerations

Comments on residues of specific veterinary drugs

Future work

Recommendations

Acknowledgement

References

Reports and other documents resulting from previous meetings of the Joint FAO/WHO Expert Committee on Food Additives

Recommendations on compounds on the agenda and further information required.

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographical references.

ISBN:

1-280-84154-0

9786610841547

92-4-068194-9

OCLC:

476039042